EXPERIMENTS WITH TUBERCULIN ON NONTUBERCULOUS COWS. 
133 
basis for estimating the effect of that agent. It will be observed 
that on April 1st, under the tuberculin there was a slight de¬ 
crease of the total solids (0.45), on April 13th, under tuberculin 
a still larger decrease (1.56), but on June 5th, under tuberculin 
there was an increase (1.01). On June 11th to 15th, without 
tuberculin there was a variation in the total solids of (1.99). 
Then as to the milk, sugar, 219 showed a percentage reduc¬ 
tion of .01 April 1st, under tuberculin, and of .61 April 13th, 
but no change whatever June 5th though again under tuberculin, 
and no change June nth to 15th without tuberculin. 
Of albuminoids 217 showed a percentage reduction of .07 
April 1st under tuberculin, but an increase of .13 April 13th, and 
of .61 June 5th. 
In fat, No. 113 had a decrease in her single test, while 212 
had an increase in all cases under tuberculin .31 April 1st, .13 
April 13th and .82 June 5th. In her entire absence of tubercu¬ 
lin June nth to 15th, she showed a variation of.51. 
With such a testimony it would be disingenious to claim any 
constant or appreciable variation as the result of the injection of 
a test dose of tuberculin, into a healthy animal, even if such 
doses were repeated several times. So far as there is evidence 
before us, everything points to the harmlessness of a single test 
dose on a sound animal system. 
