SUNDRIES AND ITEMS. 
169 
SUNDRIES AND ITEMS. 
BOVINE Tuberculosis. —The Governor of New Hampshire 
has vetoed the bill recently passed by the Legislature of that 
State appropriating $100,000, for the suppression of bovine tub¬ 
erculosis. Farmers’ vote ! 
Caution. —Cases of glanders attributed to the use of impure 
equine serum are already noted. A recent writer states, more- 
over, that “although strenuously denied, it is now well 
ascertained that several of the horses from which antitoxin was 
obtained by Aronson were suffering from glanders.” 
Whether the above assertions are true or false, it certainly 
would be well for the medical profession at large to refresh 
themselves concerning the treatment of this usually fatal veter¬ 
inary desease ; also to scrutinize the product employed. (Med¬ 
ical Age). 
DYPTHERIA ANT 1 TOXINE SERUM. 
At a meeting of the Paris Hospital Medical Society held on 
March 29th, according to the Medical Week , Dr. Variot referred 
to the fact that injections of antidiptheritics erum in doses of 
from five to ten cubic centimetres caused a rise of temperature of 
from 2.25 0 to 4.5 0 F. He said this rise was undoubtedly due to 
some “ hyperthermizing substance ” contained in the serum, and 
the problem before us was to isolate from the serum this principle 
that might become a source of danger. Dr. Le Gendre confirm¬ 
ed this experience. Prof. Hayem referred to his former experi¬ 
ments and said: “ Antidiptheritic serum obtained from a horse is 
necessarily toxic to man.” This toxity, he said, was due to 
albuminoid substances in which heat produced isomeric changes 
resulting in destruction of their noxious properties. Dr. Goug- 
euheim, while approving of the administration of antitoxine 
serum, said that it was entirely without effect, even in very large 
doses, in cases of hypertoxic diptheria. Dr. Sevestre stated that 
