PRODUCTION, OF PERIPNEUMONIA CONTAGIOSA. 
257 
EXPERIMENTAL PRODUCTION OF PERIPNEUMONIA CONTAGIOSA 
WITH CULTURES-PROOF OF THE SPECIFICITY OF 
PNEUMOBACILLUS LIQUEFACIENS BOVIS. 
By M. S. Arloing. 
(Extract from the Comptes rendus of the Academie des Sciences.) 
X. —In the two papers already published 1 had condensed 
the result of my researches upon the bacteriology of bovine 
contagious peripneumonia. In the second, particularly, I 
exposed my attempts to determine the microbe productor of 
the disease, and said that the determination of a pathogenic 
microbe was complete when by the inoculation of its cultures 
the lesions from which it proceeded were reproduced. I also 
stated then that it had been impossible for me so far to re¬ 
produce exactly—that is, with all their intensity—the char¬ 
acteristic lesions of the natural peripneumonia, or those ac¬ 
companying sometimes the inoculation of pulmonary virulent 
serosity in the subcutaneous connective or dermic tissue with 
pure cultures of the microbe I have called pneumobacillus 
liquefaciens bovis. And yet I had concluded to its specificity 
because of a series of facts observed in my numerous attempts 
to inoculate which, though of secondary value, agreed alto¬ 
gether. 
Since that time I continued my pursuit of the positive 
proof of my assertion, viz., the integrate reproduction of the 
lesions produced by the peripneumonic virus in the living 
and in the connective tissue with the cultures of the microbe 
above named. 
The doubts which had been raised upon the etiological 
value of the pneumobacillus by those among us who had 
studied the disease, urged me to furnish this demonstration, 
and especially when among the disbelievers the supposition 
was expressed that peripneumonia was probably the work of a 
living particle, escaping all the means of cultures and colora¬ 
tion actually used in the study of the known microbes. 
Working along, I had observed that the pneumobacillus, 
in its culture of bouillon, gave out toxic substances to which 
