352 
EXTRACTS FROM EXCHANGES. 
elucidated in relation to the difference in the intensity of the 
first, second or third injection.) 
2d. In cases of glanders malleine gives rise to a reaction 
even if the disease is but slightly advanced, reaction consist¬ 
ing principally in a thermic elevation of two degrees, with 
more or less large swellings. Generally there are also symp¬ 
toms of organic reaction, though not always present. When 
the disease is advanced they are well marked. 
3d. To decide if glanders exists or not, one must consider 
“(a) the duration of the elevation; that is, if it lasts more 
than thirty-four hours. In cases where t^e disease exists 
positively the thermic elevation lasts not only thirty-four 
hours, but much longer. ( b ) The thermic curvature is typi¬ 
cal in form, viz., when the rapid rising is followed by very 
slow downward motion, intermixed with one or more ris- 
• 99 
ings. 
4th. When the thermometer has risen two degrees and 
more, or when the temperature has returned to the normal 
after thirty-four hours, especially if the dropping has been 
regular, one must be careful before destroying the animal. 
Other injections are advisable. 
5th. In cases of reaction it is prudent to continue the 
thermometric observations until the fifty-eighth hour after the 
injection. To judge well of the more or less typical pro¬ 
gress of the reaction one must make his observations every 
hour and a half, after from six to ten hours following the in¬ 
jection. 
6th. If the swelling, with or without lymphatic cords, ex¬ 
ists after and more than thirty-four hours, it is, with the 
typical thermic curvature, another evidence of the presence 
of the disease. 
7th. An increase in the frequency of the pulse and of the 
respiration, with a large local reaction only, will not be suffi¬ 
cient to conclude as to the presence of glanders. 
8th. Horses in which the thermometer rises only one 
and a half degree can be considered as healthy ; those from 
that to two degrees must be regarded as suspects and be sub¬ 
mitted to a second or third injection. 
