EXTRACTS FROM EXCHANGES. 
357 
Ten injections, of 150 grains each,- of this solution may be ad¬ 
ministered without any inconvenience. The proper temper¬ 
ature may be obtained by the use of a carbonic acid appar¬ 
atus, requiring about forty seconds to bring about the proper 
; temperature, 14 0 C. Bulbs of ethyl chloride may also be 
employed.— Poit. Med. 
BEHAVIOR OF URINE WITH THE POLARISCOPE. 
Abnormal urines often rotate the plane of polarization, 
sometimes to the right, sometimes to the left. According to 
Hass, the following substances in the urine cause left-handed 
rotation: Glycuronic acid, phenyl and indoxyl-glycuronic 
acids, leucin, tvrosin, albumin, peptone, hemialbumose, cystin, 
cholestrin, aspartic acid, levulose, pseudo-butyric acid. Dex¬ 
trose is the chief and almost only substance responsible for 
dextro-rotation.— Apoth. Zeit. 
NUCLEIN THERAPY. 
After many experiments V. concluded that nuclein is a 
germ-destroying substance. By repeated trials with the nu¬ 
clein he finally was able to cure guinea pigs that had been 
inoculated with tuberculous germs. Further, the same nu¬ 
clein injected into guinea pigs rendered them non-suscepti- 
ble to the action of pneumo-cocci. In the human subject, it 
nas been used with the result of curing cases in the primary 
stages of the disease, delaying the disease when further ad¬ 
vanced, and of having no effect in advanced stages. The 
difficulties in preparing nuclein for this purpose have been 
nany, and the results obtained by the use of the remedy are 
mproved in proportion to the perfection of the process of 
manufacture. The general method of preparation is to dis¬ 
solve the nuclein from the rest of the cell by a strong alkali; 
ifter acidulating, the nuclein is precipitated by alcohol; after 
*epeatedly washing this precipitate with acid alcohol, it is 
iissolved in a solution of chemical salts similar to that found 
n the blood. In practice this solution is injected under the 
skin or into the muscular substance. It is believed that nu- 
