CONTRIBUTION TO THE STUDY OF SWINE PLAGUE, ETC. 423 
after the injection ; then, if the animal resists, it gradually and 
in a variable length of time increases and returns to its initial 
weight. In other times, the diminution is progressive and 
brings on death in from 8 to 15 days, or one month, and even 
later. I mention a few experiments : 
No. 47.—ik-600; injection of 2 cc. blood sterilized by heat; death in less than 
24 hours ; blood and cultures sterile. 
No. 63.—ik-750; injection. 2^ cc. blood sterilized with heat; death in less than 
16 hours ; blood and cultures sterile. 
No. 86.—2ks ; injection, 1 cc. blood sterilized by heat, and addition of 2 drops of 
Gram solution ; death in less than 20 hours ; blood and cultures sterile. 
No. 213.—Injection of 4 cc. of blood, diluted in about its volume of water, and 
sterilized with thymic acid ; death in 12 to 16 hours ; blood and cultures sterile. 
No. 51.—ik-960; injection of 3 cc. of blood sterilized by heat, with addition of 
6 drops of solution of Gram. The next day the weight is of ik-810; the third day 
of ik-660 ; the ninth day of ik-810. 
No. 9.—ik-575 ; 4 injections made 5 to 6 days apart, each of 1 to 1^ cc. of blood 
diluted half in water and sterilized at 58°. After the fourth injection the rabbit 
weighed ik-785. 
No. 54.—ik-835 ; injection of 2 \ cc. of blood sterilized at 58°. The next day 
the rabbit weighs ik-690. Seven days later, ik-900. Several injections of doses 
successively weaker (£ to 1 cc.) are supported without symptoms. 
No. 199.—2k-ioo ; injection of 4 cc. buillon cultures filtrated with Pasteur bougie. 
The third day the rabbit weighs ik-870; the fourth, ik-775 ; the tenth, ik-760, and 
five days later, ik-570. He dies in the night of the twentieth day. The blood and 
cultures remain sterile ; the spleen is very small. 
No. 145. — ik-900; three successive injections of 1 cc. of heated culture at 6o°; 
slight diminution of the weight. After the third injection, ik-870; five days later, 
new injection of 4 cc. of culture, and kept in the autoclast months, and afterward 
sterilized at 58°. The rabbit weighs but ik-575 on the 8th day, and ik-510 the 13th 
day; then it gradually improves and has regained its weight towards the end of a 
month. It still enjoys good health. 
No. 183.—ik-710; injection of 1 cc. of culture filtrated with Pasteur bougie; 
the next day ik-550, then ik-670, and after 12 days ik-725. A second injection 
made then of 2 cc. with same culture is followed by diminution of weight, ik-545, 
but the animal resists, and after 15 days is well. 
No. 237.—2k-i5o; injection of 9 cc. of culture filtrated with Pasteur bougie. 
The 4th day ik-945, the 7th ik-745, the 18th 1-980, after one month ik-895, after 
45 days 1-615. The rabbit died on the 57th day after the inoculation ; spleen very 
small; blood and culture sterile. 
No. 195.—2ks; subcutaneous injection oj 12 cc. of culture heated seventeen 
days for five minutes at 120° ; the 2d day ik-655, the 4th ik-S6o, the nth ik-725, 
the 21st ik-810, after a month 2ks. 
No. 338.—ik-910; subcutaneous injection of 11 cc. of culture sterilized at 120° 
during five minutes; during 11 days the weight remains between ik-520 and ik-650 ; 
the rabbit was not. observed afterwards. 
