CONFINING BITCHES FOR SPAYING. 429 
; _ V _„_:_ 
against swine plague —a small animal, weighing about 5 kilo¬ 
grammes : 
After a first injection of \ cc. of virulent culture of swine plague , made the 22-II, 
the animal became very ill; the next day he remained lying on his side; does not 
eat, and grunts instead of barking; its temperature rises from 38.4 to 40° ; this 
serious condition lasts three days. The 28-II I opened an abscess, the size of a 
nut, at the point of inoculation, and a reddish pus escapes, containing many leuco¬ 
cytes and microbes (I obtained pure culture with them); the dog soon recovers. 
The 3—III the abscess is closed ; two days later a second subcutaneous inoculation 
is made of cc. of bouillon culture of swine plague. The dog seems a little out of 
sorts for a few days following, but soon recovers without other abscess. 
The third injection of 1.5 cc. of culture is made the 12-III; and as the animal 
remains in good health, receives 1.25 cc. of virulnet blood the 14-III, and seems sick 
the next day ; eight days later, the 22-III, fifth injection of 3 cc. of bouillon culture ; 
the 24-III, sixth inoculation of 2.5 cc. of virulent blood. Following this, the dog 
is sick for several days, and has an abscess analogous to the first, which is opened 
the 27-III. The 30-III, seventh injection of 2.5 cc. of virulent blood ; very ill the 
next day, the dog eats nothing, but little by little recuperates and seems well the 
5—IV. The eighth injection is made the 19-IV ; the animal receives 3 cc. of bouil¬ 
lon culture, which he tolerates without morbid manifestations. 
This experiment proves that dogs are sensitive to swine 
plague to a lesser degree than rabbits; that they get used to 
it easier and can stand doses of virus relatively very large. 
At equal quantity, or even at an inferior one, the blood has 
produced symptoms more serious than the cultures; and it is 
not possible to tell if this is due to its greater virulency or its 
greater toxicity. 
(To be continued.) 
CONFINING BITCHES FOR SPAYING. 
By Prof. M. H. Reynolds, University of Minnesota. 
I was once asked to operate on a bitch in the country, 
where I could not even have the advantage of a table or a 
carpenter’s bench. The only thing in sight was a ladder, 
which was leaned, trough up, against the barn, on the shady 
side. The subject was tied by the hind feet to a round as 
high as the operator’s shoulder, and the front feet stretched 
down and tied to another round, the bitch on her back in the 
trough of the ladder. This proved so satisfactory that, on 
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