562 
W. SILBERSCHM1DT. 
bacilli, both the large and the small phagocytes take part in 
the fray, evidently proving that the bacillus tuberculosis is a 
formidable adversary. I bring this theory to your notice in 
the hope that we can elicit some discussion on the subject, as 
I have never heard the question considered from this point, 
and I hope to gain some information from it. 
CONTRIBUTION TO THE STUDY OF SWINE PLAGUE, HOG CHOL¬ 
ERA AND PNEUMOENTERITIS OF SWINE. 
By Dr. W. Silberschmidt. 
(Continued from page 429.) 
„ f | 
MORBID SYMPTOMS AND LESIONS OCCASIONED BY THE TWO 
MICROBES. 
Let us study first the local reaction. 
The subcutaneous injection of culture or of blood of swine 
plague gave but a slight local reaction. Generally, I made 
the inoculation of the virus at the ear so as to appreciate the 
effects better. Fresh rabbits offer a very slight local reac¬ 
tion ; after a few hours there is light hyperemia, more and 
more localized. This is still present at the post mortem, as 
well as is a local slight oedema. Upon section one observes 
a little serous liquid slightly cloudy, and the microscope re¬ 
veals the presence of a large number of bacilli with leuco¬ 
cytes varying more or less in quantity. 
This local reaction, so slight upon fresh rabbits, was very 
extended upon vaccinated rabbits, and especially in those 
which did not resist to the end. Animals which were well 
vaccinated presented at the point of inoculation an oedema 
containing after one or two days a thick pus with abundance 
of white globules and microbes, these diminishing in num¬ 
ber after a few days, though the abscess was still present. 
The better the vaccination was done the smaller the abscess 
remained and the quicker it disappeared. Rabbits which by 
preventive treatment had been but partially vaccinated, pre¬ 
sented about twenty-four hours after the injection, an oedema 
involving the entire ear, which was then drooping, and in- 
