CONTRIBUTION TO THE STUDY OF SWINE PLAGUE, ETC. 623 
itness in 40 hours. The rabbit has an oedema at the point of injection, which dis- 
ppears after four days. 24 hours after the first test, a second is made against hog 
holer a ; the witness dies in 16 hours ; this rabbit presented a small abscess localized 
> the point of injection (twelve days later, he is affected with ascending traumatic 
lyclitis ; its blood is extracted from the carotid). 
No. 183.—Vaccinated with 5.5 cc. of culture filtrated with the Pasteur bougie, 
ijected in three times ; two tests against swine plague without witness. Nine days 
fter the second test, injection of 1.20 cc. of culture of French pneumoenteritis (wit- 
ess dead in 22 days), the rabbit is losing considerable weight ; for about a month 
te remains below his initial weight and presents a tumefaction (abscess), which 
'ccupies first the whole ear, then becomes localized to the point of injection ; there 
5 besides on the back all along the vertebral column a second fluctuating tumor 
rhich seems to be a large, limited purulent collection ; notwithstanding the progressive 
ncrease of the size of this second tumor, the rabbit which did weigh ik-900 at the 
irst test weighs two months later 2k.430 and resists to an intravenous injection of 
;.io cc. of virulent blood of pneumoenteritis. 15 days later, he receives 2.10 cc. of 
flrulent blood of hog cholera, 1.10 of which kills a fresh rabbit *in 24 hours. A 
nonth later, third test against swine plague, the witness dies in less than 24 hours. 
This very interesting case, relating to an animal which has resisted to three 
druses, is specially remarkable by the strong local reaction which followed the fiist 
njection of pneumoenteritis, the application of which can only be found in the 
small dose of filtrated culture the rabbit has received. 
No. iqj .—Vaccinated by injections of diluted blood sterilized by thymic acid, 
8 cc. altogether. Resists to five tests of swine plague; the witnesses die in less than 
24 hours. 
Three weeks after the last test the rabbit receives 3.10 cc. of virulent blood of 
pneumoenteritis, and has a little localized abscess which ulcerates spontaneously , the 
witness dies the third day. Five weeks later, but of virulent hog cholera supported 
without morbid symptom, the witness dies in less than 16 hours. 
I have to relate less comparative experiments made with hog cholera and pneu¬ 
moenteritis, as I had less rabbits vaccinated against these two viruses. I mention them 
all. 
No. 284.—Vaccinated by three injections of small quantities 1.20 and 1.10 cc. 
of virulent cultures of pneumoenteritis; 12 days after the last injection he receives 
1.20 cc. of virulent blood of hog cholera y the witness dies before the 18th hour. 
The rabbit resists four days longer, and at the post mortem shows, besides a very 
large oedema of the injected ear, a marked hyperaemia and hepatized foci of two lungs ; 
the spleen is but little larger ; the blood contains hog cholera microbes and gives 
pure cultures. 
No. 232.—Vaccinated against pneumoenteritis by 5 injections, 8 cc., 75 alto¬ 
gether, of blood sterilized at 58°. Resists a test of pneumoenteritis. A month 
after, he receives an injection of 1.40 cc. of virulent culture of swine plague. The 
witness dies in seventeen hours and a half with typical lesions at the post mortem. 
This rabbit resists two days and a half, or he lives 40 hours longer than the witness ; 
no fresh rabbit resisted as long. At the post mortem one finds, as internal lesions, 
a dry fibrinous peritonitis with a great number of microbes, the intestinal serous is 
highly hyperclonic and cloudy. 1 he liver is coveted at its inferior border by a yel- 
