696 
M. R. TRUMBOWER 
I once in a while have taken recourse to was quinine), giving 
it in |- dram doses once per day to a medium-sized, full-grown 
horse, in ball shape, electuary, or rectal injection. In solution 
(drench form), it penetrates quicker, and the stomach, on ac¬ 
count of defective appetite, being more or less empty, the 
strength of the dose is not so readily determined, therefore, I 
never give it in that way. Toxical symptoms I have never 
met with. Nilitists tell us that their patients recover without 
it or any other medical interference, which 1 do not altogether 
dispute, but from experience I know that a proper dose of 
this medicament will very often relieve the sufferings of an 
animal for eight to ten hours in the twenty-four. It may even 
render it so much better that a recovery is more certain than 
his chance will be if the high temperature is permitted to have 
full sway. 
“ A short time before retiring from practice, I had a case 
of purpura haemorrhagica; head, limbs, and abdomen tume¬ 
fied ; rusty discharge from the nose; petechia, etc., were the 
most conspicuous signs. As the patient, a team horse, was 
near my place, I concluded to make an attempt with bisul. 
phate of quinia, to see what effect this remedy would have 
injected intravenous, which I introduced into the jugular by 
means of a two dram hypodermic syringe, three times on the 
first day, and twice on each the second, third and fourth 
days. By this time the swelling had so much reduced and 
appetite increased that the horse could be sent to pasture, 
where the ulceration in skin of pastern and hock joints soon 
healed, and the horse made a good recovery. It was my in¬ 
tention to repeat this experiment as soon as a suitable subject 
presented itself, in order to find out whether the good result, 
as I estimated it, is attributable to treatment, or whether it is 
mere accident; but opportunity would not favor me. So I 
am left in doubt in one respect. Am satisfied, however, that 
horses will tolerate ingredients in their circulation which are 
not exactly homogenous. 
“ Probably you remember a translation in the Review and 
Journal, of a report by Dr. Jelkman, wherein he treated ioo 
horses with a scalma-like epizootic of laryngo-pharyngitis, 
