EXPERIMENTS WITH BARIUM CHLORIDE. 
7f>5 
EXPERIMENTS WITH BARIUM CHLORIDE, 
By J. J. McCarrey, McGill University, Montreal. 
A Paper read before the Montreal Veterinary Medical Association. 
The following case reports embody the results of some 
experiments recently made by the 96 Journal Club with 
barium chloride as a therapeutic agent in the treatment of 
colic. This drug was brought to the notice of the profession 
by Dieckerhoff, who highly recommends the agent on account 
of its prompt and efficient action in producing peristalsis, and 
its low cost as compared with pilocarpine and eserine. 
Case I.— Bay gelding, aged, weight about twelve hun¬ 
dred pounds, subject for experiment. The animal in question 
received an intravenous injection of one gramme of barium 
chloride in solution. In four minutes the peristaltic murmur 
was much increased, followed by the evacuation of ffeces. In 
nine minutes another evacuation occurred and again in twenty 
minutes. The pulse and temperature were unchanged 
throughout. 
Case II.—Bay mare, weight about one thousand pounds, 
suffering from spasmodic colic. Was given an intravenous 
injection of one gramme of barium chloride in eight cc. of 
water. In three minutes after there was considerable strain- 
ng, and increased uneasiness. In five minutes the animal def¬ 
ecated, the fasces being hard in consistence. In thirty min¬ 
utes after injection fasces were again expelled and at intervals 
}f a few minutes for an hour, each evacuation being softer 
:han the preceding. Straining was marked between evacua¬ 
tions, indicating violent peristalsis. In this case there was a 
slight increase in pulsations, respiration and temperature, 
n three hours the animal showed no symptoms of colic, and 
he effect of the drug had apparently passed off. 
Case III.—Bay mare, aged. Received a subcutaneous 
njection of 1.2 grammes of barium chloride in 10 cc. of water. 
Dne minute after injection the animal appeared uneasy. In 
ifteen minutes after she commenced to strain, but no evacua- 
iori occurred till half an hour after receiving the injection. 
