TYPHOID FEVER; OR, CONTAGIOUS INFLUENZA IN THE HORSE. 
7 
results. The experiments have been made by inoculating 
blood taken at the beginning of the disease, but the results up 
to the present time are not such as would enable us to say that 
the disease can be transmitted in this way. 
Symptoms.— The disease becomes manifest after a period of 
from 4 to 7 days, is the opinion of Friedberger and Frohner, 
but this is a question I have not been able to determine posi¬ 
tively from clinical observation, as I have found animals very 
sick in the morning that were in apparently perfect health the 
night before. The symptoms vary, however, according to the 
localization of the disease. Typhoid fever may run a very 
rapid course, one case occurring in my practice when the 
animal died within eighteen hours after the first clinical mani¬ 
festation of the disease. In this case there was a rapid cerebral 
localization, which had a fatal termination before professional 
aid could be obtained, and in which was manifest an intense 
excitement and total paralysis. 
Often there is localization upon special organs, followed by 
a rapid change which may speedily have a fatal termination; 
or, on the other hand, the change is a gradual one, accompanied 
either by a pleurisy, enteritis, pneumonia, pleuro-pneumonia, 
congestion of the spinal cord, anasarca, congestion of the 
podophyllous tissue, iritis, nephritis, hepatitis, cerebritis, and 
even complications of the heart and its envelopes, all of which 
complications I have more than once seen in my own clientage. 
It is by no means uncommon to find a localization upon two 
or more organs simultaneously or successively. 
When the disease is rapid in its evolution death speedily 
intervenes if proper care is not immediately given. Animals 
will pass from perfect health into profound stupefaction and 
coma in a few hours. They stand motionless in the stall, head 
down, ears drooping, and eyelids closed; they appear to have 
lost all tangible sensibility, and from the very beginning there 
is hyperaemia of the brain and cord. At intervals localized 
muscular tumors are seen in the region of chest, shoulders and 
thighs; they will stagger and reel from side to side, like a 
