708 
A. LIAUTARD. 
United States, I found myself much embarrassed as to how and 
where to find the material necessary to my paper. To keep my 
engagement, however, I beg to ask your permission to present 
you with the history of several cases which are personal to my¬ 
self and the medical staff of the American Veterinary Hospital 
and to offer you the conclusions I derived from them. 
Among the questions that may be presented upon the use 
of malleine, taking in consideration all that has been written 
on the subject, and carefully weighing the successes and the 
failures obtained with it, and also the new questions and 
problems yet unsolved which have been brought forward of late, 
and especially in France after the experiments of Montoire, and 
in the discussion before the Societe Centrale de Medecine Veter- 
inaire of Paris, among all these questions we believe that the 
following are the most important : 
ist. What is the action of malleine when injected in healthy 
animals, in decided glanderous or suspected animals, 01 in those 
affected with other diseases ? 
2d. Is malleine infallible when used in doubtful or suspicious 
animals ? 
3d. Does malleine possess curative properties ? 
4th. Several samples of malleine being given (American, 
German and French), which seemed to keep its qualities the 
longest time ? 
5 th. At what hour after the injection is the reaction the most 
marked ? 
A glance thrown upon the tables adjoining the observations 
that I have made and recorded, will, I hope, be a sufficient ex¬ 
planation of the conclusions to which those experiments have 
brought me, and with which I will try to bring my mite in the 
solutions of the problems which are still obscure. 
1. {a.') Malleine upon healthy animals .—Our observations 
upon the effects of malleine injected into animals ‘in perfect 
health do not differ from those obtained by our European con¬ 
freres. Used by us as experiments, the results have always 
been the same—no elevation of temperature, no general consti- 
