712 
A. LIAUTARD. 
months after its arrival in this country.* In Observation 20 the 
malleine does not seem so pure, there is a slight deposit. I use 
it. however, in confirmation of an experiment made with Ger¬ 
man malleine. and of this Roux malleine I inject 15 drops brute, 
not diluted. The result of this experiment was an elevation of 
temperature almost equivalent to that obtained with the German 
malleine. A year had elapsed since I received it, and its proper¬ 
ties were the same. 
I made with German malleine, with Dr. Trautweiler, several 
observations. For some are injected 2^, for others 5 c.c. My 
colleague knew nothing of these samples, of their preparations, 
or of their strength ; he had received them from Germany, I 
believe, and we used them. 
It is thus, that in Observations 16, 19, 20, 21, 22 and 23 we 
injected 2 x / 2 c.c., and in Observations 17, 18, 24, 5 c.c. The 
results presented nothing particular. As I write this report, it 
is a year since I received that malleine, and it has yet the same 
aspect—clear, slightly citrine, and limpid. Has it the same 
qualities ? I propose to test it at the earliest opportunity. 
The malleine that I have obtained from the Bureau of animal 
industry at Washington has been tested in Observations 9, 10, 
11, 12, 13, 23, 24, 25, 26, 27, 28, 29, 30. Like the precedings, 
this preparation has given me excellent results. The last 
sample I received December 10, 1893; on January 22, 1894, it 
had lost its limpidity; had become thick. That was probaby 
due to the mode of preparation, another sample received the 
same day is yet clear and possesses the same qualities. 
However, without being desirous to decide in favor of Roux 
malleine and grant it a superiority to that of other origin, I 
think in all justice I must acknowledge that its satisfaction and 
the results obtained by its use induce me to have a certain pref¬ 
erence for it. 
* Since this paper was written we have learned that the malleine prepared by 
Dr. Roux and Prof. Nocard can be kept for any infinite length of time, under special 
condition, and that it remain always the same. 
