SOME EXPERIMENTAL RESEARCHES ON THE USE OF MALLEINE. 
849 
On the 23d he is once more injected with malleine, 1 cc. 
from Washington, without any better results or reaction. 
The three kinds of malleine have answered in the same 
manner. 
25th Observation. SUSPICIOUS.—A large brown gelding, in 
excellent condition, has been exposed, has repeated attacks of 
epistaxis; is admitted to the hospital December 15, 1893, with a 
temperature of 100 1-5°, in the evening of ioo°. The 16th he 
receives 1 cc. of malleine from Washington. 
Dec. 16, 8 a.m., temperature 100. 
4 4 
44 
10 “ 
4 4 
99 4 - 5 - 
44 
4 4 
12 “ 
44 
99 4 - 5 - 
—Swelling of the size of an egg 
44 
44 
2 P.M., 
44 
99 4 - 5 - 
4 4 
4 4 
4 “ 
4 4 
99 4 - 5 - 
4 4 
4 4 
6 “ 
4 4 
99 4 - 5 - 
4 4 
44 
8 “ 
44 
99 4 - 5 - 
4 4 
4 fc 
10 “ 
44 
99 4 - 5 - 
44 
17 , 
8 A.M., 
4 4 
99. 
—Swelling gone. 
26th Observation. GLANDERS. —Large gray gelding, be¬ 
longing to a brewery, has been sickly for two or three weeks ; 
irregular appetite; variations of temperature between ioi° and 
103°. January 19, 1894, has a slight oedematous swelling of 
the maxillary glands, a small tubercle on the left side of the 
septum, the left hock is swollen. On the 20th the tubercle of 
the septum has ulcerated and another is developing further up. 
On the 21st the temperature is 102° in the morning and eve¬ 
ning; the 22dit has raised to 103°, and he receives then 1 cc. of 
malleine from Washington. 
Jan. 
22 
4 4 
4 4 
4 4 
44 
4 4 
44 
4 4 
4 4 
44 
44 
4 4. 
4 4 
4 4 
44 
4 4 
44 
4 4 
23 > 
8 
10 
12 
2 
4 
6 
8 
10 
12 
8 
a.m., temperature 103. 
“ “ 102 4-5. 
“ “ 103. —Small swelling. 
p.m., “ 103 1-5. 
“ “ 103 2-5.—Increased and painful. 
“ “ 103 3 - 5 - 
“ “ 104. 
“ “ 104 2-5. 
“ “ 105 1-5. 
a.m., “ 103 4-5.—No change. 
