SOME EXPERIMENTAL RESEARCHES ON THE USE OF MALLEINE. 
»53 
May 
7 , 
4 r.M., temperature 
IOI 4-5. 
4 4 
4 4 
6 “ “ 
102 1-5. 
—Swelling large and painful. 
4 4 
u 
8 “ “ 
104 2-5. 
4 4 
44 
10 u “ 
104. 
—Animal very nervous and afraid. 
4 4 
8 , 
8 A.M., “ 
100. 
a 
44 
8 P.M., “ 
102. 
—Swelling smaller. 
The 9th everything is normal. 
His condition remains the same until the 13th, when he 
received 2]/ 2 cc. of malleine prepared at the laboratory of Pasteur 
Institute of New York, by Dr. Gibier. The injection was made 
in the evening at 11 o’clock, the thermometer registering 
IOI 3-5° 
• 
May 14, 
6 
A.M., 
temperature 104 3-5. 
4 4 
4 4 
8 
44 
4 4 
104 4-5. 
44 
4 4 
10 
44 
4 4 
103 3 - 5 - 
4 4 
4 4 
12 
M., 
4 4 
104 2-5. 
• 4 
4 4 
2 
P.M., 
4 4 
103 3 - 5 * 
44 
4 4 
4 
44 
4 4 
104. 1-5. 
44 
4 4 
6 
4 4 
4 4 
103 4 - 5 - 
4 4 
4 4 
8 
44 
44 
103 1-5. 
4 4 
4 4 
10 
44 
4 4 
103 i- 5 - 
4 4 
4 4 
11.30 
44 
4 4 
103. 
4 4 
15 . 
6 
A.M., 
4 4 
102 3-5. 
The swelling following the injection has run through the 
same condition; well marked at 6 A.M., it has become large, 
very large, warm, painful, with lymphatic cords, the animal has 
been very nervous and cranitive. 
At the post-mortem the only lesion found consisted in a cer¬ 
tain number of tubercles through the thickness of the lungs 
mixed with some of the translucide kinds of wound. 
Glanderous by the malleine and by the post-mortem, yet Dr. 
Gibier failed to obtain affirmative results by the cultures on 
potatoes of the contents of the tubercules from the lungs. 
J2d Observation. SUPPURATIVE LYMPHANGITIS. — A bay 
mare, 7 years old, convalescent of a severe attack of distemper, 
is found one morning with a swelling of the left thigh. She has 
afterwards all the symptoms of an attack of lymphangitis on that 
leg, and one morning a small excoriation of the coronet, from 
which escapes a small quantity of pus. She is admitted to the 
