HOG CHOLERA. 
25 
pens with sick hogs, but also in the same pens with the pigs killed 
by inoculation with pure virus. 
The next question was to expose these hogs to natural infec¬ 
tion in the most extreme manner possible. A most severe out¬ 
break of swine plague at the farm of a Mr. B. near Lincoln offered 
not only a fitting opportunity, but the severe snow storm of Nov¬ 
ember 17, in which my test hogs were snowed in with a large 
number of sick, and a dozen or more dead hogs, added to the 
severity of the test. 
EXPERIMENT. 
Five hogs that had had swine plague the previous winter at 
the college farm, four of which had been repeatedly tested as men¬ 
tioned above, and one which had not been so tested, as well as 
Nos. 26 to 32 inclusive, and two non-treated pigs, (test pigs) were 
sent to the place mentioned. Fourteen in all. 
The results of this experiment were not as satisfactory as could 
be wished for various reasons. 
First.—The smaller pigs were rather fine quality, and four of 
them were either stolen or run over by the cars which went close 
by the field where the sick drove was, and the wire fence did not 
keep the smaller ones in. 
Second.—The two test pigs and one vaccinated pig died of 
the swine plague or of the storm, but had the lesions of swine 
plague; they were found covered with snow and frozen stiff, so 
that an autopsy was made at some inconvenience. Cultures grew 
from the spleen and mice succumed to the cultures. 
Two of the inoculated pigs, being small and somewhat weak, 
died the second day after their return to the college farm from 
general exhaustion. No lesions of consequence; nor were bacte¬ 
ria to be found in them either by examination of their blood with 
the microscope or by cultivations. 
Fourth.—The five hogs from the college farm that had the 
swine plague, and been already severely tested, as well as the one 
from the same lot that had not been so tested, went through this 
exposure to infection and storm without any visible ill effects, 
though exposed for twenty-three days, and have remained well 
ever since. 
