76 
VETERINARIUS. 
developed at this point in a few days and gradually increased in 
extent, and encroached upon the underlying tissues; the base of 
the ulceration presented a grey, lardaceous appearance, and se¬ 
creted a greenish-yellow mass which stuck to the edges of the 
nasal opening. From the point of inoculation on the shoulders 
there issued at first a yellowish, then greenish-yellowish, viscid 
fluid which adhered to the hairs as it flowed over them; a lym¬ 
phatic cord the size of one’s finger extended from the nasal ulcer¬ 
ation to the corresponding intermaxillary gland. Similar cords 
were present on the shoulders extending to the axillary glands. 
In two weeks the animal presented all the characteristic clinical 
phenomena of acute glanders. However, contrary to ex¬ 
pectation, the animal gradually improved, and instead of second¬ 
ary ulcerations developing in different parts of the body, the fever 
ceased, the ulcerations did not extend, and finally manifested a 
tendency to cicatrization ; the hypertrophied lymph glands became 
smaller, so that at the end of four weeks doubts arose as to whether 
the above phenomena could be considered as belonging to glan¬ 
ders. Hr. Loeffler concluded to kill the horse, in order to ob¬ 
serve the internal conditions. The autopsy caused considerable 
astonishment. Upon the septum nasi, as well as in the immediate 
tissues between the nose and pharynx, numerous whitish and radi¬ 
ating cicatrices were found; the lungs presented old fibrous and 
calcified nodes of varying dimensions, as well as fresh noduli of 
variable size, surrounded by red rings. At the root of the lung 
a large noda surrounded a bronchus, which, on section, had a yel¬ 
low appearance, its surface being studded by a number of miliary 
greyish neoplasms, situated in a yellow gelatinous substance. A 
radiating cicatrix was present at the locus inoculationis in the 
septum nasi; the products at the same point on the shoulder were 
about the size of a hazel nut, and contained a yellow caseous ma¬ 
terial. The intermaxillary and axillary glands were somewhat 
larger than normal. All these conditions indicated that the ani¬ 
mal was the subject of a glanderous infection for a long time 
prior to the above inoculation, and the time of this experiment 
did not show any suspicious indications of any such complications. 
The above experiment being of no pathological value, owing 
