82 
YETERINARIUS. 
He inoculated two rabbits on the inner part of the ear, and in five 
or six days observed an infiltration at the locus inoculationis 
which soon became ulcers with a grayish lardaceous base; the 
corresponding glands at the base of the ear became swollen, the 
suppuration gradually ceased in one of the rabbits, leaving only 
an cedematous condition of the tissues. In the other animal the 
ulcerations gradually increased, and numerous gray nodules ap¬ 
peared in their circumference and soon underwent purulent disso¬ 
lution. These ulcerations were covered by a yellowish scab from 
beneath which a purulent fluid could be pressed. Pustulous 
eruptions also appeared in different parts of the body, but they 
soon healed. The animal became emaciated, and a snuffling res¬ 
piration, with a nasal secretion, was observed, leading to the con¬ 
clusion that the animal was undoubtedly affected with glanders. 
Both animals were killed five weeks after inoculation. In the first 
a dough-like mass was found at the locus inoculationis, the lymph- 
glands in the vicinity of the ear were swollen, but no neoplasmata 
were to be seen in the vicinity of the cut surface. In the pos¬ 
terior lobe of the left lung, which was attached to the thorax, was 
a large tumefaction with a nodulated surface and caseous con¬ 
tents ; the other parts of the lungs were free from any complica¬ 
tions. The bronchial lymph-glands were swollen and hypersemic. 
The encapsuled caseous center should not be considered as a pro¬ 
duct of glanders infections, as such conditions are a frequent oc¬ 
currence in rabbits, but they have been recorded as a participating 
phenomena in glanders. 
In the second animal, besides the already described changes in 
the ear, the lymph-glands on the head, neck and axilla were en¬ 
larged, but free from noduli. In the lungs a few isolated gray 
noduli could be seen. The spleen was enlarged and of a reddish- 
brown color. The mucosa of the septum nasi of the right side 
presented a small ulceration with swollen edges and lardaceous 
base, underneath which a number of small noduli were about to 
conglomerate ; the adjoining tissues were very hyperaemic. 
In order to see if the injection of pure cultivations of glanders 
bacilli into the circulation of rabbits would produce a general in¬ 
fection of miliary noduli, as is the case in tuberculosis, a subcu- 
