GLANDERS. 
103 
fiuence of one of its members, and that through him a path 
lies open which the human school can only follow in, but never 
initiate. Thus veterinary medicine is beginning to assume its 
proper place in the country. As a last word, we can only say 
that we earnestly hope that the regents of this university, who 
have seen fit to retain our colleague, will find no reason of becom¬ 
ing dissatisfied with the course they have pursued, and beg to 
assure them that every earnest member of our profession is with 
them in their desire to establish veterinary medicine upon the 
only true foundation—the scientific. 
ORIGINAL ARTICLES. 
GLANDERS, 
By Yeterinarius. 
A Contribution for the Prize offered by the U. S. Veterinary Medical Astociation 
for Papers published in the American Veterinary Review. 
(Continued from page 83 .) 
The Inoculation of Guinea-Pigs with Glanders Bacilli. 
Dr. Loeffler experimented with eighty-five animals. The 
virus was introduced into the side of the abdomen by cutting 
through the skin with a pair of sterilized scissors and making a 
pocket with a steel needle. Each animal was placed in a separate 
box and they were then put in an isolated room. Not a single 
07ie of the inoculated guinea-pigs remained exempt from infection. 
The course of the inoculated disease varied in the different ani¬ 
mals. At the locus inoculationis little was to be seen during the 
first two or three days. The edges of the wound were either ad¬ 
herent or covered with a thin eschar and slightly swollen. About 
the fifth day the locus inoculationis became tumefied; the edges 
of the wound hyperaemic; separated and secreting a purulent fluid 
eventually leading to the formation of yellow scabs. Finally an ex¬ 
tensive ulcer developed with swollen edges and a purulent larda- 
ceous base. The glands corresponding to the parts involved be- 
