210 
VETERINARIUS. 
develop in other organs, sncli as the liver, kidneys, heart, and also 
in muscles, bones, etc. Such a dyscrasis is by no means a per¬ 
manent condition, as, when infectious elements gain access to the 
blood, they must soon be removed by natural processes, from the 
fact that they find a resting place in certain tissues or organs, 
where they develop metastatic centres or pass away with the se¬ 
cretions, urine, etc. The latter was confirmed by numerous ex¬ 
periments. If the disease continues in certain parts, it is self-evi¬ 
dent that the tendency to metastatic processes must also continue. 
Processes in the anterior respiratory passages and skin often heal, 
and the lymph-glands undergo a retrograde metamorphosis and 
retract, and that the secondary metastatic processes are only ob¬ 
served after the lapse of a considerable time. This period is often 
spoken of as “ latent glanders ”—that is, the disease is present in 
invisible organs—pulmonary glanders. If a horse should be killed 
at this time, no striking pathological changes except those in the 
lungs are found ; slight changes in the anterior respiratory organs 
often heal without leaving an easily recognized cicatrix, and the 
tumefactions in the lymph-glands disappear quite as often, especi¬ 
ally when the inflammatory processes are of a non-specific charac¬ 
ter. Such cases have led to the mistaken assumption of the exist¬ 
ence of primary pulmonary glanders. It is also well known that 
this latent or hidden form of glanders often gives rise to secondary 
infection, the development of new local centers, and a suspicious 
pneumonia, which render the disease again open to occult demon¬ 
stration. Such cases may possibly have led to the assumption of 
the spontaneous origin of glanders. 
The specific glanders noduli in the lungs always appear in 
numbers, never as single phenomena; at first they are of a gray 
color, and moist, but later they become yellow, and dry in charac¬ 
ter. They either lie subpleural, so that they can be seen through 
the same, or in the substance of the lungs ; they develop in the 
stroma or interstitial tissue of these organs. The fresh noduli are 
surrounded by an irregular zone of inflamed parenchymatous 
tissue, the circumferences of which are not sharply defined. 
These zones are hypersemic, moist, atalectatic, and present a 
smooth surface or section, though they are sometimes granulated 
