GLANDERS. 
211 
fibrinous pneumonia. Tlie nodules are separated from the pneu¬ 
monic surrounding by a ring of red tissue. In passing the fingers 
over such a lung, one can not only feel the noduli specific to glan¬ 
ders, but also the pneumonic centers surrounding them. The num¬ 
ber of noduli present varies; in some lungs they are present in 
thousands, sometimes disseminated, sometimes in nests so thick 
together that the infiltrated pneumonic centers coalesce, and large 
sections of the lungs are transformed into a dense and atalectetic 
mass. The noduli and their surroundings soon undergo certain 
changes. The gray noduli become opaque and yellow, surrounded 
by a transparent gray and vascular tissue, which can be traced to 
its connection with the interlobular tissue and the septa of the 
alveoli. 
These yellow centers are slightly caseous, but do not present a 
thoroughly desiccated appearance; their circumferences are irreg¬ 
ular, and interrupted by the extension of processes of a like char¬ 
acter into the fibrous surroundings; so that these noduli cannot be 
removed, even with a knife, without tearing the tissue in which 
they are situated. When a confluence of a large number of noduli 
takes place, large sections of the lungs are transformed into masses 
of grayish-wliite indurated tissue, enclosing necrobiotic noduli in 
their midst; upon section, these noduli appear as small yellow 
centers, surrounded by a sort of capsule with irregularly marked 
outlines. At other times these centers are of a purulent charac¬ 
ter, surrounded by infiltrated pulmonary tissue, which is often 
complicated by softening disturbances that began in the specific 
product of glanders, giving rise to the formation of cavities of 
variable size and form, filled with a purulent or soft-like mass. 
New eruptions may be seen in the vicinity of these centers, which 
are valuable in recognizing the specific nature of the disturbance. 
At other times disintegrated masses are found surrounded by a 
pale gray layer of fibrous tissue forming a sort of capsule ; cross- 
section reveals the existence of cavities and canals, filled with 
purulent and necrotic material. The ulcerative processes fre¬ 
quently lead to the erosion of blood vessels and sequential haemor¬ 
rhages ; the latter are, however, often prevented by the formation 
of thrombi in the vessels—a very common occurrence in the lungs 
