MALADIE DU COIT-DOURINE. 
245 
while in other cases they are increased in size and their softened 
tissue becomes of a gray, red or even brown color, and pseudo- 
tuberculous and purulent cavities have been found in them. The 
spermatic cord and the epididymis are thickened and surrounded 
with deposits of yellowish matter, gelatinous in consistency and 
of hyaline aspect. 
These local lesions are often associated with ansemia and a 
general loss of flesh. The heart and the large blood vessels are 
flabby, and the blood unctuous and adhesive, with a diminution 
in the proportion of the red globules. The intermuscular cellular 
tissue is filled with a yellow, gelatinous infiltration, and the flesh 
is soft and easily torn. Serous infiltration, and at times indura¬ 
tions, are found in the subcutaneous cellular tissue. The neuri- 
lema of the large nervous trunks of the paralyzed legs contains 
tumefactions, and these are surrounded by a thick infiltration. In 
many cases there is also infiltration over both the spinal marrow 
and the encephalon, and the whole cerebral and spinal mass is 
more or less softened. There is a loss of transparency in the 
arachnoid, and sometimes a large accumulation of serosity is 
found in the sub-arachnoid space. 
For the cause of the metastatic diseases which are found in 
the testicles and the lungs—more often in the latter—we know 
we must lo*ok to the lesions of complication, such as the articular 
•manifestations, or those arising from purulent infection. 
VTI. Etiology .—We have already said that the disease is 
only seen in breeding animals, and that it is communicable only 
by the act of copulation. In districts where it appears it is there¬ 
fore generally easy to trace the infection of the mare to the stal¬ 
lion by which she has been covered. And reciprocally, a healthy 
stallion may in the same manner derive the disease from an in¬ 
fected mare. 
Nothing positive is known as to the spontaneous development 
of this disease, and it cannot be ascertained with any degree of 
assurance whether the abuse of the genital function of the male, 
or the existence of a vaginal catarrh in the female, can be con¬ 
sidered as occasional causes. There are authors, like Haubner, 
who admit that it might arise from a chronic affection of the 
