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PROF. ROBERTSON 
taken twice daily for eleven days. From these latter observa¬ 
tions it was found that the heat regulating function was scarcely 
disturbed. 
On the 25th of November, from the death by a natural attack 
of quarter-ill of one of the nninoculated calves, and of another 
heifer at Hodnet, an opportunity was given to test the efficacy of 
intravenous inoculation. In the presence of several interested 
gentlemen, some of whom had witnessed the inoculations on the 
12th, Mr. Penberthy injected, with all antiseptic precautions, 
into the subcutaneous tissue of the limbs of the remaining seven 
calves a considerable quantity of virulent matter taken from the 
muscle of a still warm heifer which had died from quarter-ill. 
The seven animals were then placed and kept together in a meadow 
under identical conditions. The results of this testing were: Of 
those inoculated intravenously on the 12th of November, none ap¬ 
peared to suffer in the slightest degree; of the three unprotected, 
two sickened on the 26th, one of them dying on the 27th, the 
other on the 28th. Both of these, on being examined after death, 
were stated to have exhibited well-marked lesions of quarter-ill. 
The third of the unprotected calves showed, on the 28th, a crepi¬ 
tating swelling at the seat of inoculation, and was dull and unwell 
on the 30th; a well-defined swelling existed at this spot, which 
gradually softened on the subsequent days, the calf returning to 
a state of health. 
In order to prove the practicability of the intra-venous method 
of inoculation, on December 22d, Prof. Penberthy, with the aid 
of Mr. Tomes, the bailiff of Hodnet, inoculated as described 
twenty-four young cattle. The operation lasted about an hour 
and twenty minutes. On this occasion, in every case the injection 
was done by piercing direct through the skin into the lumens of 
the vein. These animals, Major Percy reports, have shown no 
signs of indisposition after the inoculation, nor have any cases of 
quarter-ill appeared amongst them. 
The practical outcome of this work appears to be, that it ha- 
made clear the fact of the communicability by inoculation of the 
disease known in England as quarter-ill,” and its identity with 
that treated by MM. Arloing, Cornevin and Thomas, as u charbon 
symptomatique.” 
