352 
.T. t). HOPKINS. 
time there appear on the mucous membrane of the vagina, vulva 
and clitoris, small miliary pustules, which soon become little su¬ 
perficial ulcers, no more than one-fifth of an inch in diameter. 
These ulcers are not long in cicatrizing, but they are replaced by 
others which, like the first crop, are more numerous in the fossa 
navicularis, on the clitoris, and near the margin of the vulva. 
These symptoms are intermittent, disappearing for some days and 
again manifesting themselves; in the majority of cases becoming 
milder, until they finally disappear. 
In the malignant form in the mare we have the same symp¬ 
toms as in the benign ; uterine excitement, slight swelling of the 
lips of the vulva, redness of the mucous membrane, discharge, 
etc. After three or four weeks the symptoms become more ac¬ 
cused ; the tumefaction of the vulva increases and diminishes b} T 
turns; sometimes it remains limited to the labia and inferior com¬ 
missure ; at other times it descends in the perineal region to the 
mammae; and at other times, again, it is nuelateral, and gives a 
deformed appearance to the vulva. 
The mucous membrane is red and swollen, with more or less 
deep colored patches and conspicuous wrinkles, and the miliary 
pustules and cicatrices already described ; while the temperature 
of the vagina is increased. 
On the external surface of the labia, the perineum and the 
inner face of the thighs, there are often ecthymatous lenticular 
pustules, which are succeeded by small circular sores that readily 
heal. 
There is vaginal catarrh, the matter being viscid, glutinous, 
dirty white in appearance, and frequently possessing a strong 
odor. This discharge is increased after coitus , during fits of 
coughing, exercise, and the emission of urine, which it either pre¬ 
cedes, accompanies or follows. It adheres to the hair, soils the 
tail, perineum, inner surface of the thighs and hocks, and, in dry¬ 
ing, forms yellow or brownish crusts. 
At a later period it is endowed with irritating properties, due 
to the presence of a free acid, and causes depilation of the coat at 
those parts it comes in contact with ; then it changes its charac¬ 
ter, becoming thick, purulent, of a yellow or reddish color, and 
gives off a strong, disagreeable smell. 
