484 
Jf. W. STRICKLER. 
scarlet fever. On January 12, 1884, I injected under the skin of 
his arm a small quantity of the virus. A short time thereafter 
the cervical lymphatic glands became enlarged and tender to the 
touch. There was no marked systemic disturbance, neither was 
there any sore mouth or throat. All signs of glandular enlarge¬ 
ment and tenderness had disappeared in six or seven days. He 
was then taken to a house in which there was a boy sick with 
scarlet fever. The disease was in the desquamating stage and the 
throat still sore. His parents being poor, the pillow upon which 
the patient lay had not been exchanged for a clean one since the 
beginning of the sickness. This pillow was placed over the face 
of the boy who had been inoculated, and held there some time. 
He was then made to inhale the breath of the patient, and after¬ 
ward to remain some time in the sick room. The boy did not 
develop scarlatina after having been thus exposed, neither has he 
contracted the disease since, although there has been opportunity 
for infection. 
Case II.—B. P-, aged four years; had never had scarla¬ 
tina. On March 6th I inoculated her in the arm (hypodermi¬ 
cally) with a small quantity of the foot-and-mouth virus. On 
13th her temperature rose to 103° F. Her mouth was sore, with¬ 
out showing any vesicles, and she complained of a pricking sen¬ 
sation in her throat. She had slight headache, the appetite was 
impaired, and she was quite peevish. There was no eruption at 
any point on the body. By March 20th she was well. She was 
then taken to a house where I had a patient in the desquamating 
stage of scarlet fever. The patient was very sick at the time be¬ 
cause of complications; indeed was so ill that I felt somewhat 
doubtful about the issue. The same plan of exposure was adopted 
as in the first case, although I could not succeed in getting the 
inoculated child quite near enough to the patient to inhale her 
breath; but the “ pillow exposure ” and the length of time she 
was in sick room afforded a good opportunity for infection. She 
did not subsequently develop scarlet fever. 
Case III.—J. M-, aged ten years; had never had scarlatina. 
1 inoculated him just as I did the first two. He did not after¬ 
ward develop any systemic disturbance or local lesion. After a 
