492 
.T. W. STR1CKLER. 
Med. Journal, 1863, p. 711.). “It is a very general opinion 
among continental veterinarians that, when the milk can be 
boiled without coagulating, it is no longer dangerous to use; and* 
Hilderbrandt, in Magdeburg, expressly states that he never obser¬ 
ved a single case of injury to health from the use of milk which 
had been boiled without coagulating.” (Gurlt u. Ilertwig's Mag¬ 
azine, vi., p. 179). 
It is certainly true that the two diseases (“ foot-and-mouth dis¬ 
ease ” and the “ Hendon cow disease”) are very similar in some of 
their clinical features. This will be made manifest when the 
mode of development and subsequent history of the vesicles which 
are characteristic of the two diseases shall have been compared. 
In the following notes some points of similarity between these 
two affections may be incidentally noted. 
When at Deering, Me., some time ago, for the purpose of 
studying foot-and-mouth disease in cattle, I saw one or two cases 
which could very easily have passed for “ bovine scarlatina,” as 
described by Drs. Klein and Cameron. The vesicles and ulcers 
upon the teats and udder were the exact counterpart of the word- 
picture of those seen upon the Henden cows’ udders and teats. 
Just here I may say that during the last four years I have 
been endeavoring to determine : 1st, Whether scarlatina can be 
generated in the lower animals by inoculation with human scarla¬ 
tinal virus; 2d, if so, whether such a disease is mild in character; 
3d, whether virus furnished in such a manner could, by inocula¬ 
tion, be used as a means of preventing the development of scarlet 
fever in human beings. 
To determine the truth concerning the first inquiry I obtained 
some blood from a patient who had scarlet fever, and injected 
thirty drops of it into the right jugular vein of a colt about one 
year old. I also introduced under the skin of the thorax a blood- 
clot obtained from the same patient, and caused the colt to swal¬ 
low about two drachms of pharyngeal mucus. This occurred on 
May 1, 1883. The temperature gradually rose from 101J° F. 
(the temperature of the colt before inoculation) till it reached, on 
May 12th, 1021 F. During the following night the colt lacerated 
the skin of the chest to a small extent, and immediately thereafter 
