496 
,T. W. STRICKLER. 
reputation and skill as an investigator place him very high in our 
esteem and confidence, tells me that cows inoculated with scarla- 
linal micrococci of human source become affected in 'precisely the 
same manner as the Henden cows had been. The disease he re¬ 
fers to has the following characteristics, viz.: Upon the teats and 
udder vesicles or bullse appear, from five to seven days after the 
commencement of the disease. In number they vary from two to 
four on a teat, and range in size from a pea to a horse-bean, and 
contain as first a clear fluid. The first vesicle frequently appears 
between the two fore teats, close to the abdominal vein. These 
vesicles usually become broken in milking, leaving raw sores, 
sometimes red, in other cases pale in color, with raised, ulcerated- 
looking edges. Shortly after the vesicle becomes ruptured a 
brown scab forms upon the sore. A thin watery fluid exudes from 
under the scab. The skin about the eyeballs is puffy, and is said 
to present a minute red eruption or rash. There is also an erup¬ 
tion on the liind-quarters. This eruption in its later stages con¬ 
sists of patches of eczematous-looking crusts, which, when picked 
off, leave a raw, moist sore. The hair comes away with the scab. 
There is no pitting of the skin. There is sometimes a discharge 
of yellow matter from the nostrils and eyes. The fever is moder¬ 
ate. Sore throat is said to occur in severe cases. The bowels 
are loose in very acute cases. There is a dry, husky, irritative 
cough, with bronchial rales and quickened breathing in some 
cases. In December, 1885, it was reported that a sudden and ex¬ 
tensive outbreak of scarlet fever had occurred in South Marylebone, 
and that it appeared to be associated with the distribution of 
milk from a particular retailer. It was afterward discovered that 
tire milk w T as obtained from cows affected with the disease just 
described. There were in all about one hundred cases of scarlet 
fever caused by drinking the infected milk. If, then, it be true 
that the Henden cows furnished a contagium which caused the 
development of genuine scarlatina in about one hundred persons, 
it must be true that the cows had scarlatina ; and again, if the in¬ 
oculation of cattle with human scarlatinal virus produces a disease 
identical with the Henden cow disease, it follows that scarlet 
fever can be generated at will in susceptsble animals. 
