172 
W. L. WILLIAMS. 
referred to, was made. In remembering what they did then, 
we have inferred that the entire body of alumni might, with 
propriety, be called upon, and, judging by the very few 
answers that have already reached us, we have every reason 
to believe that the amount required will finally be donated. 
If we are disappointed in this expectation, we intend still to 
persevere in this line of work and reach, some time, a success¬ 
ful issue, if such a thing is practicable. 
ORIGINAL ARTICLES. 
THE PATHOLOGY OF AZOTURIA 
AS SUGGESTED BY ITS HISTORY AND SYMPTOMS. 
By W. L. Williams, V. S. 
A paper read before the joint meeting of the Indiana and Illinois Veterinary 
Medical Associations. 
The number of theories as to the pathology of azoturia is 
limited only to the number of those who have written upon 
the subject, each writer apparently entertaining different 
views, so that it can well be said that there is no generally 
accepted doctrine as to its intimate nature, and we may add 
that each theory so far offered is open to more or less serious 
objection. 
The most uniform and serious objection to all the theories 
so far proposed, is their essential lack of harmony with the 
preparatory and clinical history of the disease, the cardinal 
facts in the origin of which are : 
ist.—The disease is the immediate result of more or less 
severe muscular exertion. Some authors, it is true, merely 
say that such muscular activity generally precedes the attack, 
but it may safely be said to always be the case. 
To accomplish this muscular exertion, the animal need not 
but generally does leave the stall. It may be brought about 
in the stall by the animal becoming cast, or by anything which 
may cause sudden muscular excitement. 
2d.—This exertion must take place after a rest extending 
