ANTIRABIC INOCULATIONS. 
191 
also developed the fact that sponges washed with water alone, 
held, thereafter, fewer germs. Baruchello, in testing the 
power of the corrosive-hydrocholic mixture, showed that 
pieces of sponges left in this solution for two hours, and after¬ 
ward placed in the culture glasses, gave absolutely no colo¬ 
nies. He recommends that the sponges be washed with 
water and then thrown in the above mixture, which is to be 
kept in a tub; they are allowed to remain therein until 
needed. This mixture is cheap; the sponges are not ruined 
thereby ; there is no danger of poisoning or infection to man 
or horse, provided that the liquid be not imbibed ; the sponges 
are always sterile. 
ANTIRABIC INOCULATIONS. 
MECHANISM OF IMMUNITY. SENSATIONS PRODUCED BY 
THE ANTI-HYDROPHOBIC PASTEUR INOCULATIONS, AS 
DESCRIBED BY INOCULATED SUBJECTS.* 
By Paul Gibier, M.D., Director of the New York Pasteur Institute. 
More than ten thousand people have been inoculated dur¬ 
ing the five years in which the Pasteurian inoculations have 
been practiced. Among the number were a few doctors; 
nevertheless there does not, so far as my knowledge goes, ex¬ 
ist any detailed narrative of the phenomena noticed in those 
who were submitted to the preventive treatment for rabies 
after having been bitten. I have therefore thought that it 
o o 
would prove interesting for the study of immunity in general, 
and as a contribution to the history of this system of treat¬ 
ment in particular, to make known some of my observations. 
Following in the steps of several doctors—either directors 
or assistants in antirabic institutions—who did so to ward 
against a possible accidental inoculation during their daily 
manipulations of virulent matter—I inoculated myself as well 
as two of my assistants. A young lad attached to the labora¬ 
tory was likewise inoculated. But I must here and at once 
* A paper read before the N. Y. County Medical Association, May, 1890. 
