194 
PAUL GIBlER. 
two assistants and myself experienced, during and after the 
inoculations, a series of phenomena indicating that certain de¬ 
partments of the nervous system were stimulated into activity 
by some unusual excitement. 
For my part, during the days when I took the last inocu¬ 
lations, and a few days after, I observed a greater activity of 
the salivary glands. Several times a day I felt saliva welling 
from the sub-maxillary glands and from the parotid canals, 
my mouth filled with saliva and I was obliged to eject it. 
During the night I was obliged to urinate, which is not my 
usual custom. These symptoms were the same in the case of 
my assistants, which evidently shows a sign of excitation of 
the medulla oblongata. 
1 recall that in 1884, in a pamphlet on hydrophobia* I have 
shown that polyuria was a frequent symptojn of rabbits inocu¬ 
lated with the virus of hydrophobia, at the moment their ner¬ 
vous system was invaded by the germ. 
During the last w r eek of the treatment, and the week fol¬ 
lowing, I felt a certain heaviness of the head and an inability 
. to work. These symptoms were experienced by Messrs. Roger 
and de Monchy, with these additional ones: on the fifth day 
(inoculated with the marrow of the sixth day) Mr. Roger 
complained of a sudden pain in his right side, lasting about 
half an hour. On the eighth day (inoculated with the mat¬ 
ter of the fourth day) he experienced dizziness which lasted 
intermittently for fifteen days. The twelfth day he felt pain in 
the lumbar region, extending as far as the right testicle. On 
the fourteenth day the vertigo continued, accompanied by 
buzzing in the ears, which rendered walking difficult. But 
since this treatment Mr. Roger assures me that he has been 
relieved of a chronic dyspepsia accompanied by pyrosis. The 
aivine functions are also more regular. 
Mr. de Monchy was more affected by nervous troubles. 
From the second injection he felt pains in the nape of the 
neck; on the fifth day this pain spread into the brachial plex¬ 
uses. After the ninth inoculation some lulgurating pains 
* Recherches sur le rage et sur son traitment.—Asselin & Honzeau, Paris. 
