' 588 
PAUL GIBIER. 
the osseous system, and causes degeneration of a destructive 
character. From our present knowledge, it would be folly to 
attempt treatment. Prevention, however should be aimed at, 
and during the last six months I have made an effort to have 
all animals showing the slightest suspicious symptoms of 
osteo-porosis, removed to other stables, and in all stables where 
the disease appeared repeatedly I have had the floors taken 
up, and two or three feet of urine and manure-saturated soil 
removed, the old flooring-boards and sleepers carefully clean¬ 
ed and disinfected, and a new supply of good, fresh sandy soil 
put down before the floors were replaced. In cases where it 
was possible to have the floors raised twelve or eighteen inches 
from the ground, I have strongly advocated to owners the 
advisability of doing so. As these preventive experiments 
have been tried by me for the limited period of six months 
only, I am not prepared to say at this time that they are of 
any special benefit. 
PEROXIDE OF HYDROGEN AND OZONE. 
THEIR ANTISEPTIC PROPERTIES. 
A Paper read before the International Medical Congress, held at Berlin, Ger¬ 
many, on the 7th of August, 1890. 
By Dr. Paul Gibier, Director of the Pasteur Institute of New York. 
Gentlemen : Since the discovery of peroxide of hydro¬ 
gen by Thenard, in 1818, the therapeutical applications of 
this oxygenated compound seem to have been neglected both 
by the medical and the surgical professions; and it is only in 
the last twenty years that a few bacteriologists have demon¬ 
strated the germicidal potency of this chemical. 
Among the most elaborate reports on the use of this com¬ 
pound may be mentioned those of Paul Bert and Regnard, 
Baldy, Pean and Larrive. 
Dr. Miguel places peroxide of hydrogen at the head of a 
long list of antiseptics, and close to the silver salts. 
Dr. Bouchut has demonstrated the antiseptic action of 
peroxide of hydrogen, when applied to diphtheritic exuda¬ 
tions. 
Prof. Nocart, of Alfort, attenuates the virulence of the 
