A NEW PARASITIC DISEASE OF CATTLE. 
635 
farm, were also changed with the same effect as upon the 
first farm ; in all ten calves and one heifer died. 
In January, 1889, the same disease appeared on a third 
farm in the vicinity of Jutland, causing the death of fifteen 
calves, the majority of which succumbed after but one day’s 
illness. They were suddenly attacked, could not stand, and 
took no food or water; dyspnoea appeared and the afflicted 
died in a few hours. Post-mortem revealed an oedematous 
infiltration of the pharyngeal and laryngeal cavities ; enlarged 
spleen and altered blood, and in some a phlegmonous inflam¬ 
mation in the posterior portion of the buccal cavity. In one 
calf was found an abscess upon the inside of the left cheek 
with phlegmonous infiltration of the adjacent tissue. Veter¬ 
inarian Meyer, who had given me the foregoing history of 
his cases, also sent me a few portions from the organs. 1 
found the ovoid bacteria in all of these specimens; further, 
two rabbits which had been inoculated therefrom, died in ten 
or twelve hours under the usual symptoms. One of the sick 
calves upon this farm was removed to another and so the 
disease was transported to the fourth farm, on which ten 
calves died. 
White and ordinary mice died in twenty-four to forty- 
eight hours after inoculation ; after death examination showed 
swollen spleen with dark blood and many large, but neverthe¬ 
less characteristic ovoid bacteria. Rabbits died after twelve 
to twenty-four hours as a rule, but often after ten or twelve 
hours under symptoms of acute septicaemia ; post-mortem ex¬ 
aminations always showed a hemorrhagic inflammation of the 
trachea, with usually an enlarged spleen and a hyperaemic con¬ 
dition of the kidneys, liver and intestines; in the blood and- 
spleen the same ovoid organisms occurred in surprising quan¬ 
tities ; these were so numerous in some cases, as to occlude 
the larger capillaries of the mesentery. 
On the 25th of January, 1888, a dog was injected upon the 
lateral portion of the neck, with one-half ccm. of bouillon cul. 
ture of the calf plague (the fifth consecutive culture from the 
spleen of a calf); during the subsequent lew days the animal 
became feverish, and at the point of injection there appeared 
