202 
JOHN T. SHANNON. 
to demonstrate its presence in all cases of uncomplicated in¬ 
fluenza. 
As a result of these bacteriological researches they now manu¬ 
facture an antitoxin for this disease. Like all febrile diseases, 
it has a period of incubation, which varies from a few days to a 
few weeks. One attack does not produce immunity. 
Symptoms .—The symptoms of influenza vary considerably 
in intensity and form. This is due to the disease attacking dif¬ 
ferent parts at different times. Any organ or organs may be 
attacked, and, as a matter of course, the leading symptoms de¬ 
pend upon and are governed by the organ most severely affected 
—the temperament of the animal, etc. 
One of the first symptoms is dullness—languor. Slightest 
exertion causes fatigue; increased pulse, 48-72; temperature, 104- 
108; respiration, 30 to 60; constipation, congestion of the con¬ 
junctiva, legs cold. The duration depends entirely upon the se¬ 
verity of the attack—from a few days to weeks. 
Treatment with Antitoxin .—The influenza antitoxin is not a 
specific for the disease, but in a great many cases it will arrest 
the disease and cause it to run a shorter course. The modes of 
administration: First, intravenously, followed by some dan¬ 
ger. Second, subcutaneously; is for the best, as there is no dan¬ 
ger. The only precaution necessary is to cleanse the parts when 
you make the injection with some reliable antiseptic solution. In 
the last few years I have used over six hundred doses as a pre¬ 
ventive, even after the disease had appeared on the farm, with 
good results. 
On one farm the manager would report a colt sick—not eat¬ 
ing, dull and a temperature which would last a few days—and 
another animal would show the same symptoms. I inoculated 
all the animals, which amounted to seventy-five, with influenza 
antitoxin. They were sale animals, two years old. They were 
then shipped to New York City and sold, and only one animal 
contracted influenza, I have done this for the same farm three 
years in succession, all young animals, two years old, and they 
have not lost a single animal, and only took one out of the sale 
