266 
EDITORIAL. 
V. Betegh is more interesting. It relates to the etiology of the 
disease. 
In his contribution, which I find resumed in Leclainche’s 
Revue , he first examines concisely the recent researches on the 
question, recalling the works of Loffler, Nocard and Roux on 
the filtrability of the virus. He reminds principally the fact that 
the virus does not go through a Kitasato’s filter, a fact which 
may give points in relation to the size of the agent of aphtous 
fever. 
Dr. L. V. Betegh has found, in the preparations of Term, 
the eosinophile corpuscles which this author considered as the 
agents of the disease. Betegh had difficulties in finding analogous 
corpuscles, and those that he found he hesitates to consider as 
identical to those of Terin. 
He has not found in the blood of sick animals the Cytor- 
rhyctes that Sieged discovered and cultivated. 
* The investigations of Betegh rested on the following con¬ 
siderations : The virus exists principally in the aphtse, as their 
contents diluted to 1-5,000 is still virulent. The agent of the 
disease is not ultra-microscopic, as it does not go through a Kita¬ 
sato’s filter, and that through this, colloids will pass whose gran¬ 
ules are yet visible and measurable. Again, it seems very im¬ 
probable that the smallest microbes should be smaller than the 
colloidal granules upon which they feed. 
Betegh takes also exception on account of the facts that the 
microbes of pleuro-pneumonia, and Negri bodies of rabies, pass 
through filters, having forms which are visible with the micro¬ 
scope, as well as some trypanosomes are also, in an appropriated 
condition, able to pass through filters. 
Examined with a dark room microscope (ultra-microscope), 
the lymph of apht?e shows a large number of small, rounded, 
very mobile corpuscles. Those can be seen in the leucocytes, 
round the nucleus, in the periphery of the cells, and sometimes 
in the nucleus itself. These elements may be colored with the 
Giemsa, according to L. V. Betegh. 
After coloration, these corpuscles seem to be formed of a 
