302 
D. E. SALMON. 
“ October 6. There is irritation and thickening of the 
mucous membrane. Application repeated. 
“ October 8. Inflammation increased. Application renewed. 
“ October 9. There is now a small sore at the point where 
the arsenic was applied. Application repeated. 
“ October 10. The sore in the nostril is about half an inch 
in diameter and appears like a superficial erosion. Application 
repeated. 
“ October 12. The sore is somewhat largerstill superficial. 
Application repeated. 
“ October 13. There are now two ulcers in the nostril be¬ 
coming confluent; also, a fissure extending along the floor of the 
nostril and following the course taken by the slight flow of nasal 
secretion. A careful comparison of these lesions with ulcers 
developing naturally, in the nostrils of horses at pasture on the 
same ranch, indicates that their appearance is identical in every 
respect. Application repeated. , 
“ October 14. Application repeated. 
“ October 15. The ulcer is now i /4 inches long by 1 inch in 
breadth. It is covered with thick, black crusts and is just suffi¬ 
ciently moist on the surface for the dust from the hay to adhere 
and form these crusts, but there is little if any suppuration. There 
is still a fissure below the ulcer. 
“ The lesion resembles the naturally formed ulcers of three 
other horses on pasture on this ranch, and, after close com¬ 
parison and study, it was concluded that their appearance was 
identical in every respect, even to the fissures below, the ulcers. 
As the ulcer was so well marked and characteristic, no further 
applications of the arsenical paste were made. 
“ November 2. The ulcer is still about i/d inches in diam¬ 
eter, with the crusts becoming loose around the border. The 
animal was killed and the nose taken to Butte, where it was 
entered as an exhibit at the hearing.” 
The ulceration, in this case, began within a week from the 
first application of the arsenic, and a large, deep ulcer was de¬ 
veloped within two weeks. This was also about the rate of devel- 
