PROTOZOIC STOMATITIS OR SORE MOUTH OF DOGS. 
337 
lesions, stained by Jenner’s method, reveal the presence of a 
protozoic infection of the mucus glands, which is associated with 
pyogenic streptococci. These are found in the glands themselves 
and also in the tubes near the surface. I have also found them 
in small numbers in the muco-purulent exudate. These parasites 
invade the mucus glands as the Dermodex follicidorum invade 
the sebaceous glands, and likewise are associated with pyogenic 
infection. My experiments thus far do not permit me to attempt 
to classify the protozoa; however, I will describe it as best I may. 
I find them to be actively motile, possessing a movement indica¬ 
tive of bi-polar flagella, reproduce by simple division, will grow 
on artificial media, presence of chromatin granules, non-sporu- 
lating, io m. in diameter, 40 m. in length; stained specimens 
from pure cultures frequently appear as crescent shaped on ac¬ 
count of their movement; stain with any of the aniline stains; 
easily demonstrated in tissue sections stained by Jenner’s method 
of staining protozoa; shape resembling a grain of barley; in¬ 
jected into the mucous membranes of healthy dogs will produce 
the disease, from which it may be again obtained. 
Granting that this is the etiological factor in sore mouth, the 
next great question arising is the successful method of treatment. 
Since my experience has led me to conclude that the general 
systemic disturbances are produced by the absorption of the toxic 
products of the parasite and accompanying pyogenic bacteria, I 
have directed treatment along that line. 
About the first thing I do to a case is to flush out the bowels 
with cold enema of normal salt solution, which reduces the tem¬ 
perature and assists in the elimination of the toxines already 
absorbed. Next I remove all mucus and diphtheritic membranes 
with cotton and inject into the mouth full strength of hydrogen 
peroxide, which cleanses the surface and opens up all mucous 
ducts, thereby allowing free escape of any retained toxines. I 
then give a dose of bacterin made from the associated pyogenic 
organisms. I continue the peroxide treatment three or four times 
a day and the enema as often as necessary to keep the tempera¬ 
ture down. If the general symptoms indicate the need of stimu- 
