ARSENICAL POISONING FROM SMELTER SMOKE. 
390 
temperature 102. i° F. Repeated the dose, but the animal only 
ate a few mouthfuls and did not ingest more than one-tenth of 
the arsenic. 
September 3. General appearance improved, but has no ap¬ 
petite; drinks little and walks very stiffly. Mucous membranes 
red, pulse almost imperceptible, artery tense, temperature 100.8°. 
Endeavored to give 40 grains of arsenic in solution by injecting 
it with a syringe into the pharynx. About three-fourths of it 
was ingested. 
September 4. Animal very dull, drowsy, without appetite, 
drinks little, excrement soft like that of cows, visible mucous 
membranes much congested. Artery at the jaw is tense and full, 
but pulse is small and weak, scarcely perceptible and could not be 
counted. Heart beats, quick, jerky, but not violent, 87 per 
minute; respiration 21; temperature 100.7°. Difficulty of move¬ 
ment has increased until the animal is hardly able to walk. En¬ 
deavored to repeat the close, but only about one-half was in¬ 
gested. 
September 5. Weakness, drowsiness and paralysis more 
pronounced; mucous membranes very red; respiration easy, 21 
per minute; heart beats quick, well-defined, 87; temperature, 
99.8°. No symptoms of pain. No arsenic administered. Died 
at 10 a. m. 
This horse died in seven days from the administration of the 
first dose. The total quantity of arsenic which it was attempted 
to administer was 260 grains, or 37.1 grains per day. The esti¬ 
mated quantity ingested was 194 grains, or 27.7 grains per day. 
This animal was severely poisoned in four days with 140 grains 
of arsenic, 20 grains of which were in powder; that is, an aver¬ 
age of 30 grains a day in solution and 5 grains in powder. 
Cornevin (8) gives an account of the experiments of Cocconi 
and Schappe on the influence of arsenic in fattening of rumi¬ 
nants. They commenced with bovine animals with daily doses 
of 0.1 gram (1.54 grains) of arsenite of soda and gradually in¬ 
creased to 1 gram (15.4 grains). Larger doses could not be 
given without the appearance of symptoms of poisoning. 
