426 
D. J. MANGAN. 
justifiable. This method is based upon a well-known scientific 
interpretation of autoinoculation in the spontaneous cure of in¬ 
fectious diseases. The brilliant results that I have witnessed 
after the application of this treatment has made me feel that to 
ignore it in pyogenic infections would be nothing short of criminal 
neglect on my part. 
We may assist in bringing about a natural cure, or, in other 
words, specific antibodies may be developed, by direct inoculation, 
or by placing the autogenous toxic substances, developed during 
the course of the disease, directly into healthy tissues. This is 
the autotherapeutic method of cure. 
Duncan's definition of autotherapy is: That therapy which 
employs all of the autogenous nascent , toxic substances developed 
during the course of the disease against which the tissues react in 
a curative manner. 
The reaction against these toxic substances is the reaction 
against the disease. 
When the infecting agents have been changed by growing in 
a culture media outside of the body tissues or by time, their thera¬ 
peutic value is lessened in proportion to the change that takes place 
in them by the various processes which they undergo. 
Duncan has proven that in extra-alimentary and extra-pul¬ 
monary diseases, if the toxic product of the disease is placed in 
the mouth it will tend to develop specific anti-bodies, and in intra¬ 
alimentary and intra-pulmonary diseases, if the toxic products 
of the disease be placed in healthy tissues outside of these systems, 
it will tend to develop specific anti-bodies. It must be remem¬ 
bered that it is healthy tissues that develop specific anti-bodies. 
It is desirable to autoinoculate in many diseases : just how many, 
clinical experience alone will tell. 
Pus contains all the toxic products of tissue changes, enzy¬ 
mes, ferments, and chemical changes in the protoplasmic molecule, 
against which the healthy tissues react in a curative manner. Be¬ 
sides the pus and necrotic tissues being the ideal culture medici, 
they contain the toxic substances derived from the causative 
bacteria. 
