AUTOTHERAPY IN THE TREATMENT OF SEPTIC DISEASES IN THE HORSE. 427 
It has been shown when bacteria are in the blood stream (as 
it is claimed, bacteria have been found there in rheumatism in 
man), they develop few anti-bodies, but when injected subcutan¬ 
eously they develop many anti-bodies. 
Duncan likens autotherapy to a two-edged sword. It is doubly 
useful if handled by intelligence, but great harm may be done in 
the hands of the ignorant and careless. Autotherapy is not a cure- 
all ; neither is any other therapy. 
I have administered the crude pus to horses by three different 
methods. 
First Method .—One c.c. to 3 c.c. of pus (necrotic tissue) de¬ 
pending upon the density of the discharge to 20 c.c. or 30 c.c. of 
water, mixed well in test tube, pass through a bunsen or alcohol 
flame until the solution begins to show a coagulation or curdling 
of its contents, then filter through a triple layer of sterile gauze; 
add one drop of phenol; 1.5 c.c. to 2.5 c.c. of the filtrate would 
be injected into the loose cellular tissue in the pectoral-axilary 
region. The dose graded according to the condition of the ani¬ 
mal. The second dose not to be given for at least 48 hours, de¬ 
pending upon the clinical symptons of the case; seldom would I 
administer the second dose in less than four days. 
Second Method —One tablespoonful (15 c.c.) of pus (if not 
enough pus collected can use the necrotic tissue, which is obtain¬ 
able by scraping the parts), add enough water to make 6 oz. (180 
c.c.), mixed throughly, and it is advisable to dispense it in a 
brown container so that the attendants do not become familiar 
with the contents. Give 1 oz. (30 c.c.) every hour until four doses 
are taken. Repeat if necessary the same dosage from three to six 
days later. In the meantime collect and save as much discharge 
from the wounds as possible, so as to be provided for future 
dosage. 
Third Method .—One c.c. to 3 c.c. of pus, depending upon its 
density, to 20 c.c. or 30 c.c. of water, shake well and permit the 
container to remain at about room temperature for eight to twelve 
