autotherapy in the treatment of septic diseases in the horse. 429 
blood do not have free access. Any agency that will increase the 
local blood supply is indicated. 
When the beneficial effects of the first dose or treatment of 
the autogenous antigen is passing off, then it is time for another 
dose or treatment. 
It is well to remember that as recovery progresses, intervals 
between the application of the treatment are gradually lengthened. 
Most vaccine-therapists have discarded the opsonic count and 
rely entirely on careful observations of the clinical signs as the 
indicators for dosage. 
The most important point to be remembered is that the earliest 
application of the vaccine or antigen will give the greatest num¬ 
ber of cures, and as their administration does no harm, one should 
not hesitate even if the septic condition appears insignificant, par¬ 
ticularly in our class of patients.- If we wait until a pronounced 
permenent “ negative phase ” developes and the animal is in a 
generalized septic state, our results will not be very successful, but 
nevertheless hope should not be abandoned; the antigen may be 
administered in a very small, highly diluted doses, at very short 
intervals. 
The recital of case reports are, as a rule, very tiresome and 
unsatisfactory to the listeners, but I ask you to bear with me for 
a short time while I relate briefly the results obtained in some 
cases that covered a wide field of infection. 
Case A To. i.—Gray gelding of the draft type, having a large 
fluctuating fistulous abscess on the right side of the withers. Two 
doses of the heated pus were administered subcutaneously, the 
first given on October the 18th, and the second on October the 
22d, 1911. The discharge took on a sero-sanguineous aspect the 
following day after the first injection. The animal made a com¬ 
plete recovery within two weeks. No microscopical examination 
was made of the discharge. 
Case No. 2.—Bay gelding showing a very severe infection of 
fore point of the fetlock on the off fore leg. Microscopical ex¬ 
amination revealed the presence of the necrophorus bacilli, strep- 
tococcis and staphylococci. Multiple abscesses were forming 
