o24 
CHARLES H. DUNCAN. 
gall bladder, and it has been known for very many years that 
phosphatic calculi form in the urine as the result of changes pro¬ 
duced by bacteria. It is only going one single step further to 
search for a bacterial cause in every case of urinary calculus and 
to try to identify the bacterial cause, if such should exist. I have 
not undertaken any systematic observation along these lines, but 
again, in the course of our daily routine work a certain number 
of facts, which all point in one direction, have thrust themselves 
on my attention.” 
12. “Bacteriuria. —A medical man who had suffered for 
years from a bacteriuria, which furnished in every case a pure 
culture of staphylococcus, developed a real calculus and was op¬ 
erated on. (The question arises, had the staphylococcus been 
discovered early in his urine”—and given by the mouth, ‘‘whether 
the operation could have been avoided). 
Dr. Wright gives three other cases of renal calculus where 
cultures from the catheter developed staphylococcus. Dr. Wright 
says: 
13. “Pruritus Ani is again one of those disorders which 
the ordinary man would not think of referring to bacterial infec¬ 
tion. At any rate, it had not occurred to me that it might be due 
to such an infection till a patient who was suffering from this 
condition was referred to me for treatment, of an associated 
furunculosis. I now find it difficult to understand how it is pos¬ 
sible to look at pruritus ani from any other point of view than 
that of a bacterial infection. I have had, in observation and 
treatment, in addition to the case just referred to, three other 
desperate cases of this infection. In each case I have found that 
a platinum loop applied to the seat of irritation brought away 
quite astonishing numbers of microbes invariably staphylococcus, 
pseudo-diphtheria and occasionally tetragenus, and in each of 
these cases life has been rendered comfortable, or at anv rate 
quite tolerable by the use of proper vaccines.” 
The disease that can be relieved by placing the above named 
micro-organisms in the mouth are those diseases which are com¬ 
plicated by them, as cancer, and some cases of eczema, etc., etc. 
