82 
A. LIAUTAKD. 
materials, for example, by using inflammation-of-the-spleen and scepticaemic 
bacilli in the case of mice. Also tuberculosis and inflammation-of-the-spleen can 
exist simultaneously in the same animal. I have inoculated a number of guinea 
pigs which were tuberculous to a great degree with inflammation-of-the-spleen 
bacilli. In consequence of this, the animals were attacked with inflammation of 
the spleen and died. Several of them had very large numbers of tuberculous 
bacilli in the lungs and spleen, and in sections from these, by double coloring, 
the tuberculous bacilli took the blue, and the very numerous inflammation-of-the- 
spleen bacilli took the brown color. As a further instance of a spontaneously 
arising mixed infection, the occurrence of micrococci herds in typhus is to be no¬ 
ticed. Further, Brieger and Ehrlich* have drawn attention to a combination of 
typhus with malignant oedema, in which case the very fitting expression mixed 
infection was first used. It is therefore plain that we have such a mixed infection 
in the case here spoken of. The tuberculous disease of the bronchial glands 
formed the primary infection, which, in consequence of the rapid growth of the 
bacilli and their forcing themselves into the arteries, led to general miliary tuber¬ 
culosis. Not until this disease was well established, the strength of the organism 
had been very much lowered, and therewith probably the ground for the micro¬ 
cocci invasion had been prepared, did the latter follow; proceeding to all appear¬ 
ance from an ulcerated defekt (imperfection) on the tongue, and causing in 
connection with the miliary tuberculosis, death so much the more quickly. 
A similar combination of tuberculous bacilli in the miliary tubercles of the 
lungs, and micrococci in the neighboring vessels, has been observed by Watson 
Cheyne, f and it may therefore probably be accepted that with a little attention 
this sort of mixed infection might be not infrequently found. 
Of the other case of miliary tuberculosis coming under examination, the fol- 
owing may be briefly sketched : 
* Berl. klin. Wochenschrift 1882. No. 44. 
tThe Practitioner, Vol. XXX. No. 4, Apr., 1883, p. 295. 
{To be continued.') 
RECORDING CLINICAL OBSERVATIONS. 
By Pkof. A. Liatjtakd, M.D., Y.M. 
A Paper read before the United States Veterinary Medical Association. 
Mr. President and Gentlemen : 
Not long since, in reading an English veterinary paper named 
the Veterinary Record , my attention was attracted to a paragraph 
heading an article of that excellent hebdomadary, which 1 thought 
contained a suggestion of great value, and which it seems to me 
all veterinarians and especially, perhaps, those of America, might 
