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R. KOCH. 
tinctorially as the sorts described, and that with the help of aniline reaction one 
would be able to distinguish these sorts of bacilli easily from others. The 
animal in which the bacilli with staff-shaped spores were found, died and had, 
as the dissection showed, beside numerous tubercles in the lungs, spleen, etc., 
several tuberculous abscesses in the intestinum tenue abundantly supplied 
with tuberculous bacilli. 
From the cases of phthisis examined I will speak of a few which served 
as points of departure for inoculation and for the culture of tuberculous 
bacilli. 
1. —A woman of thirty years, whose mother also died of phthisis, suffered 
for half a year from cough with expectoration. Great loss of flesh. Occasion¬ 
ally slight fever. Death after three months’ stay in the hospital. Dissection 
showed left lung partially deformed as well the upper as the under lobe contain¬ 
ing a number of communicating vomicae. Right lung also deformed, containing 
a large baylike vomica in the upper lobe and several smaller ones in the 
middle lobe. Spleen, liver, kidneys free from tuberculous changes. Under 
microscopic investigation only a moderate number of bacilli were found in the 
contents of the vomicae. In the surroundings of the vomicae, which had com¬ 
pact walls, were giant cells grouped around little nucleousless herds and 
largely supplied with tuberculous bacilli. 
2. —Man twenty-three years of age. His mother said to have suffered from 
phthisis. Had been in the hospital the year before on account of pleurisy. In the 
last few months repeated haemoptisis. Besides this diarrhoea. At his reception 
into the hospital thin, anaemic. Suffocation and bronchial breathing over the 
point of the right lung. Cough with purulent expectoration. Death after four 
months. In the right lung large vomicae with partly callous, partly caseously 
infiltrated walls. On the vocal chords tuberculous ulcerations. Beginning 
amyloid degeneration of the spleen. Numerous abscesses in the intestines, 
swelling and caseous degeneration of the mesentric glands. Also in this case 
the tuberculous bacilli were present in comparatively small numbers in the 
contents of the vomicae and in the lung tissue, but, on the contrary, were very 
numerous at the base of the intestinal abscesses and in the caseous mesentric 
glands. 
3. —Workman of forty-three years, quite strongly built. No heredity could 
be proved. Had suffered for three months from cough, expectoration and in¬ 
creasing weakness. Of late his troubles, especially dyspnoea, had grown much 
worse. Death after twelve days’ stay in the hospital. In the tips of both lungs 
vomicae of moderate size, wide-spread caseous infiltration with occasional 
softening and formation of vomicae in the middle and lower parts of the lung. 
Ulceration in the larynx. In the vomicae as well as in the caseously infiltrated 
lung tissue, bacilli were found in great quantities. 
4. —Man of thirty-two years, not hereditarily burdened. Said to have been 
sick only four weeks. At his reception into the hospital anaemic, emaciated. 
Death after six weeks’ stay in the hospital. In both lungs numerous vomicae 
of varying size whose surroundings for a considerable distance were caseously 
infiltrated. Some smaller vomicae lay near the surface and showed as slight 
protuberances. These were used to obtain rein culturen. 
