THE MANIA FOR INNOVATION IN THERAPEUTICS 
228 
herence, often absent; nasal discharge double, thin, yellowish- 
colored matter and mixed with blood. Nasal membrane in¬ 
jected with a yellowish infiltration or covered with petechial. 
Nasal ulcers isolated and circular or conglomerated, forming 
a large irregular wound, borders tumefied and injected ; bot¬ 
tom of ulcers granulated, red and bleeding on the lightest 
friction. Sometimes these ulcerations penetrate to and 
through the nasal cartilage, establishing a communication of 
both cavities. All ulcers enlarge in a short time, and between 
them the nasal membrane is infiltrated wdth a fibrinous or 
albuminous substance, that becomes soft and causes mortifi¬ 
cation of the membrane on a very large surface. 
There are always lenticular buttons, that mark a begin¬ 
ning chancre. Acute glanders always causes death in about 
six days. 
(To be continued). 
THE MANIA FOR INNOVATION IN THERAPEUTICS. 
By T. W. Turner, Ph.G. 
At no time in the history of medicine have there been so 
many remedies offered to the medical and veterinary profes¬ 
sions as in the present decade. Every new medical discovery 
is first published in some trade journal, which claims for it 
superior physiological properties. The recorded cases in 
which the new remedy may have proved a success are dili¬ 
gently investigated, it is tried wherever possible, the pros 
and cons of its merit widely discussed, till it is in its turn sur 
perseded by something newer, and before much is known 
about the remedy it is—forgotten. 
This constant passion for new therapeutic remedies, which 
may at times embarrass the professions, sometimes proves a 
benefit to suffering man and beast. This tendency of the 
times to produce or invent something new is felt in materia 
medica as well as in every department of intellectual life. 
The vegetable remedies, such as roots, herbs, seeds, barks 
which in former days occupied the most prominent place in 
pharmacology, have been gradually replaced by the products 
