248 
J. P. KLENCH. 
» 
that it is impossible for this State to get rid of this contagious 
element within the next few years, especially as there is no 
authority existing in this State that has the legal power to 
enforce proper and complete disinfection of the infected 
premises, besides burning the body of the diseased animal. 
From the above description of the differential symptoms, 
I form the following conclusions as to the possible glanders: 
1. That the mule disease in California is, originally, not 
the chronic farcy, on account of the complete absence of in¬ 
duration in all the pathological formations —no hard, adherent 
gland, no indurated nasal ulcer , no chronic glanders, no hard, in¬ 
durated cords and ulcers on the skin, no chronic farcy. 
2. That although there exists a very great analogy of 
symptoms, it cannot be either the acute glanders or farcy, 
because the mules resist this affection many months, and the 
horses even longer, while the confirmed acute glanders causes 
death in about six days without fail. When farcy causes 
death, the post mortem examination will always show the 
lesions of acute glanders in the nasal cavity and lungs, as also 
of supperative arthritis. On the contrary, I have never dis¬ 
covered any lesion of metastatic or inflammatory origin in 
the lungs nor in any other viscera of the several mules I have 
examined after death. 
On the other hand, it is an admitted fact that the acute 
glanders and farcy select in preference animals of a sanguine 
constitution, and especially the jackass and mule, stallions and 
well bred horses, which are naturally more excitable than the 
phlegmatic, cold blooded horse. It has been repeatedly proved 
that chronic farcy inoculated from a horse to a jackass, never 
developed the chronic glanders, but always the acute form, 
and caused death in a few days. Now the mule has evident¬ 
ly inherited a portion of this natural aptitude to contract the 
acute form in all internal diseases ; and, indeed, mules suffer¬ 
ing from a chronic internal affection are very, very scarce. 
It is well known that thousands of mules were affected in this 
State and lived for several months, some of them even keep¬ 
ing up a good condition for along time, so that this circum- 
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