294 
P. PAQUIN. 
Lincoln, III., June 6, 1889. 
J. H. Rauch , M.D ., Springfield. 
Dear Doctor.—In reply to Dr. Paul Paquin’s letter, forwarded to me and 
herewith enclosed, I first saw the case mentioned, (H. S. Pierce affected with 
glanders), in November, 1887. Mr. Pierce was under my observation from that 
time till April, 1888. When first seen he had a “ running sore ” on the left arm 
at front of elbow, one near the left knee and one near the left ankle. Much 
stiffness and considerable swelling of the limbs involved. 
For local treatment I used iodoform powder on the ulcers and applied rub¬ 
ber bandages. Internally, Syr. Fer. Iod. f. 3 j. t. d. and Fowler’s solution, be¬ 
ginning with m. v. t. d. for two days, then m. vj. two days, and so on till ten 
drops were taken, then decreasing the dose in reverse order and repeating. 
I take pleasure in reporting that Mr. Pierce has completely recovered his 
health. He is free from stiffness in the limbs and has his normal strength. His 
complete freedom from symptoms has now continued just about one year. 
Courteously, 
L. L. Leeds, 
Per K. 
The other case is one now in charge of Dr. Griffith, mem¬ 
ber of the Missouri State Board of Health, Kansas City, Mo. 
He contracted glanders in 1887, I think, and is still living. I 
saw Dr. Griffith in May at the Missouri Medical Association 
meeting, Springfield, Mo., and he informed me that the pa¬ 
tient is doing fairly and at work. His lymphatic system, 
however, is still affected and presents chronic lesions. The 
case and its history I know well through Dr. Griffith, and it 
is undoubtedly glanders. Now as to my own case I will 
neither assert nor deny that it was glanders, but the trouble 
I know was due to inoculation of matter from a mare which 
had glanders decidedly pronounced. The same matter inoc¬ 
ulated to two guinea pigs by a student here, killed one some 
fifteen days or so afterwards and the other in about six weeks. 
Both died in my absence, and as I had left in great hurry and 
had made no arrangements for preserving the specimens or 
for close examination, I cannot say what was the cause of 
death ; besides I was not told of the death of the guinea pigs 
until after my recovery. The mare died, as did three other 
horses and mules on same farm, all from glanders. 
It was on the 22d day of March, at Lees Summit, Mo., 
that the accident occurred. While examining the mare just 
mentioned, she blew her nose, and a great deal of matter cov- 
