398 
M. ARLOING. 
duced into the connective tissue the bacilli divide themselves 
unequally between the blood and the lymph, and find their 
way into the lymphatic glands, the parenchymatous organs, 
and the serous membranes ; these manifest their presence at 
first in the points which show themselves most favorable to 
their stagnation and to the development of the process that 
they engender. 
Tuberculization of the lung occurs in the rabbit as well 
after inoculation of the virus into the jugular vein as into the 
subcutaneous connective tissue of the thigh. And since in 
this animal the lymphatic path followed by the virus is not 
forcibly marked out by the tubercular lesions, it is impossible 
in the presence of a rabbit affected with pulmonary tubercu¬ 
losis to know whether the bacilli are disseminated by means 
of the blood or the lymph. 
Assuredly, when the virus penetrates by the intestine, the 
lymphatic glands are generally invaded in the first place, then 
the lesions extend to the serous membranes of the thoracic 
cavity ; but the infection does not march invariably in this 
manner; it can evolve simultaneously in the abdomen and in 
the lung. In order to gain the organs rapidly the virus must 
be thrown into the blood at a very early period. 
When the lesions are established in an organ, and have 
manifested themselves, it is not necessary that they should be 
either very extensive or softened in order to throw into the 
circulation a certain quantity of microbes. The sudden ex¬ 
plosion of most cases of meningitis or of tubercular peritoni¬ 
tis coincidently with pulmonary lesions of slight extent and 
but little advanced, furnishes the proof of our assertion. 
An animal that presents any tuberculous focus whatever 
is constantly in imminent danger of generalization, and noth¬ 
ing shows at the moment of slaughter for the butcher that 
the capillary network of the muscles is not traversed by the 
bacilli in search of a place propitious for their multiplication. 
The distinction between a localized and a generalized tu¬ 
berculosis is very difficult to draw. 
The indication of a generalizalion is found in the presence 
of lesions of the lymphatic glands outside of the lymphatic 
system of the organs tuberculized. 
