HISTORY OF CONTAGIOUS AND INFECTIOUS DISEASES. 
565 
Starting from the boundary of Poland, where it never to¬ 
tally disappeared, it spread into Germany, where it caused 
great devastations, especially in Thuringia and Saxony ; in 
1728 it invaded Brandenburg and in 1729 Austria; in 1730 it 
broke out again in Saxony and extended to Istria, Friaul and 
the Venetian States. It spread still further in 1735—*36. A 
Venetian bulletin issued on the 9th of October, 1735, an- 
nounced that the plague existed in Friaul, Basanese and Tre¬ 
vigiano. December 3, of the same year, it already had spread 
over Verona, Brescia, Crema, Mantua, and Milan; shortly 
after it entered the Roman district and the Piedmont, where it 
remained till 1739. 
Between i74o-’5o it spread again over all Europe. Start¬ 
ing from Hungaria it quickly entered Bohemia, Bavaria, and 
southern Germany, remaining there till 1745. 
In 1742 it was brought into the Lorraine. In the same 
year it entered, from the Swiss side, the Dauphine and Franche 
Compte, and in 1745^46 caused fearful losses throughout 
France. It entered Saxony and Thuringia again in 1746. It 
was carried into Italy through Piedmont, during the wars of 
I744~’45, and through Menetia, when it first ceased in its ter¬ 
rible career in 1749. Its fearful power was most felt in FIol- 
land in 1744-46, when over two hundred thousand head of 
cattle perished. In England the epidemic broke out in the 
vicinity of London, whence it spread over the whole king¬ 
dom, lasting there longer than in any other country; first les¬ 
sening in 1758. Isolated outbreaks occurred even as late as 
1780. During the third year of the epidemic, killing the in¬ 
fected animals was again tried with but little effect; although 
eighty thousand cattle were killed in that year alone. Not¬ 
tinghamshire and Leicestershire lost over forty thousand head 
in 1747, while Cheshire lost thirty thousand in six months. 
In 1745-49 the cattle-plague arose in Denmark and 
Sweden, 1747-’53, in Curland and Livland, and 1750 in Prus¬ 
sian Lithuania. Isolated outbreaks, embracing but little ter¬ 
ritory, were observed in 1757 in Minden (2), where it was 
brought by the French army, and also in 1758-’59 in Branden¬ 
burg, Europe’s total loss in cattle between i740-’5ois estb 
