I 
28 REPORTS OF CASES. 
halter and bit the wound severely, putting it quite back to 
where we started. We then tied the animal securely in a 
large box stall, discontinued the blanket and oakum pad, and 
used a tonic powder of zinc oxide, fuller’s earth and carbolic 
acid. It granulated slowly for a few weeks, and then as¬ 
sumed a very indolent character. 
On October 31st we practiced skin grafting, placing 
thirty-six little islands of skin on the ulcer, and keeping the 
parts sprayed with salt solution several times a day. 
We placed the animal in slings for support and to prevent 
his rubbing the wound again. The grafts remained firm for 
four days, when about half of them came off. . Gradually 
they all loosened and came away, but the wound looked in 
better condition. 
We then used a collodion dressing, beginning on Decem¬ 
ber 27th. The wound made good progress with this treat¬ 
ment until January 13th, when the horse broke the slings 
during the night and lacerated the wound in an ugly manner. 
We were pretty thoroughly disgusted, as can well be 
imagined, but having gone thus far, we decided to see it 
through. We replaced the slings and kept him in them all 
the time except about thirty minutes a day, when he was 
taken out to be exercised. We next tried quinine sulphate 
and got a very rosy, healthy wound with it, but at the end of 
a week it did not improve as well us under collodion, so we 
returned to that treatment. 
One day, when in conversation with Prof. Roscoe Bell, of 
Brooklyn, we mentioned our case, spoke of how many drugs 
we had tried, and how discouraging treatment seemed to be. 
He said that he had obtained good results with pepsin and 
suggested that we try it. 
Beginning the pepsin treatment on January 29th, we could 
see improvement in three days, and a week later the wound 
was cicatrizing nicely. It continued to granulate rapidly and 
steadily until March 10th, when it was perfectly healed and 
covered by solid cicatricial tissue. 
